Haloperidol For Outpatient Symptom Management in Patients Diagnosed With Cannabinoid Hyperemesis Syndrome in the Emergrency Department

Trial statusNot yet recruiting
Trial phaseEarly Phase 1
Trial typeInterventional
Biological sexAll
Age18+
SponsorUniversity of Illinois at Chicago

About this trial

Patients diagnosed with cannabinoid hyperemesis syndrome that are safe for discharge from the emergency department will be sent an outpatient prescription for haloperidol to be used as needed at home. The study goal is to see if having this medication available helps to prevent return emergency department visits for recurrent or persistent symptoms.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Age ≥ 18 years

Primary ED complaints of acute or episodic nausea, vomiting, and/or abdominal pain

Self reported frequent cannabis use

History of recurrent, cyclical episodes of severe nausea and vomiting

Disqualifiers

Patients with imaging or lab findings suggestive of an alternative etiology that would explain their symptoms

Already on dopamine agonist/antagonist therapy for another condition

Parkinson's disease

Lewy body dementia

Trial design

Design model

Single group

Treatments tested in this trial

  • Haloperidol

    Drug

    This intervention involves providing patients an outpatient prescription for as needed haloperidol to attempt to control symptoms of cannabinoid hyperemesis and to attempt to prevent return to the emergency department for that reason.

Treatment groups

100 Participants
are divided into 1 treatment group
Group A: Patients who will receive haloperidolExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Rate of return to the emergency department

The investigators plan to measure the percentage of people who return to the emergency department for recurrence of symptoms attributable to cannabinoid hyperemesis syndrome

Time frame
1 month

Secondary outcomes

1

Improvement in symptoms

The investigators plan to report patient reported change in symptoms attributable to cannabinoid hyperemesis syndrome. The subjects will report change in their symptoms via a 5 point likert scale with 1 being no change in symptoms at all and 5 being complete resolution of symptoms.

Time frame
1 month
2

Medication side effects

The investigators plan to report the rate of patient reported side effects that are considered attributable to cannabinoid hyperemesis syndrome

Time frame
1 month

Other outcomes

Sponsors and contacts

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This trial is not recruiting at the moment. You can still explore other options: