Imaging Mitochondrial Complex-I in Cocaine Use Disorder: a [F-18]BCPP-EF PET Study
Trial statusRecruiting
Trial phaseEarly Phase 1
Trial typeInterventional
Biological sexAll
Age18-45
SponsorRajesh Narendran
About this trial
Studies proposed in this application will image mitochondrial Complex-I in cocaine use disorder (CUD) and matched healthy controls
Eligibility criteria
Qualifiers
Males or females between 18 and 45 years old.
fulfill DSM-5 criteria for moderate or severe (4+ criteria) cocaine use disorder.
No lifetime DSM-5 schizophrenia, schizoaffective disorder, bipolar disorder, and developmental disorders.
No comorbid DSM-5 major depressive or severe anxiety disorders (including cocaine-induced mood and anxiety disorders) in the past 12 months.
Disqualifiers
None
Trial design
Treatments tested in this trial
- [F-18]BCPP-EF
Treatment groups
40 Participants
are divided into 1 treatment groupSponsors and collaborators
Rajesh Narendran
Lead sponsor
University of Pittsburgh
Sponsor institution
National Institute on Drug Abuse (NIDA)
Collaborator
Source ClinicalTrials.gov