About this trial
Reflux and the aspiration of gastric contents have always been important focal points. Previous study stated that trauma is an important factor in aspiration pneumonia.
Often, emergency trauma patients have residual gastric contents due to the ingestion of food before injury, the accidental swallowing of nasal and/or oral blood after injury, and delayed gastric emptying due to stress, pain, or the use of opioids.
During sedation or general anesthesia, such satiated patients are often at risk of aspiration due to a reduction in lower esophageal sphincter tension and the protective inhibition of the airway reflex.
Perioperative gastric ultrasound can be performed at a bedside ultrasound unit; it can safely, non-invasively, conveniently, and effectively evaluate the fullness of a patient's stomach and the nature of their gastric contents.
It can also be used in the selection of an appropriate method for the anesthetic induction process and can reduce the risk of vomiting, aspiration, and related complications.
As a gastric motility-promoting drug, metoclopramide can accelerate gastric emptying.
Dexamethasone reduced the incidence of nausea and vomiting and improve gastric motility.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Traumatic patients undergo emergency operations
18-60 years of age
155-180 cm in height
Body mass index <30 kg/m2
Disqualifiers
A history of diseases of important organs, such as diabetes, gastro-paresis, liver and kidney dysfunction, and cardiopulmonary insufficiency.
Contraindications for metoclopramide or dexamethasone treatment.
Taking opioids or drugs that affect gastric motility.
A history of esophageal, gastric, or upper abdominal surgery.
Trial design
Parallel
Treatments tested in this trial
Dexamethasone
Combination productIV infection
Ultrasonography assessment
Diagnostic testAssessment of gastric motility by ultrasonography
Treatment groups
Trial outcomes
Primary outcomes
Assessment of gastric weight/volume kg/m^2 measured by ultrasonography in traumatic patients.
Assessment of gastric weight/volume kg/m\^2 by grams measured by ultrasonography in traumatic patients.
Locations
Sponsors and contacts
Click on the lead sponsor to view all of their trials.
Ahmed Nassar Ibrahim Mohammed
Lead sponsor
Assiut University
Sponsor institution
Assiut University
Collaborator
This trial is not recruiting at the moment. You can still explore other options: