Ketorolac Versus Corticosteroid Injections for Sacroiliac Joint Pain

Trial statusRecruiting
Trial phaseEarly Phase 1
Trial typeInterventional
Biological sexAll
Age18+
SponsorMcMaster University

About this trial

This study will contribute to the current literature that have compared joint injections with steroid versus ketorolac providing evidence for the use of ketorolac for SI joint pain. Currently steroid is the clinical standard for joint injections, however with repetitive use, steroid injections can damage the joint. Ketorolac is an alternative anti-inflammatory medication that does not cause the same joint damage and at a cheaper cost than steroid. The investigators hypothesize that ultrasound guided SI joint injections utilizing ketorolac provide the same pain relief as corticosteroid SI joint injections measured at 2, 6 and 12 weeks post injection. This would allow more frequent injections to control pain at a decreased cost to the healthcare system.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

SI joint pain for at least 3 months

Age greater than 18

Must have at least 3 special tests positive for SI joint pain on physical exam

Disqualifiers

Previous back surgery

Radicular leg pain

Discogenic pain

Myofascial pain syndrome

Trial design

Design model

Crossover

Treatments tested in this trial

  • Methylprednisolone Injection

    Drug

    Medication will be injected into SI joint under ultrasound guidance

  • Ketorolac Injection

    Drug

    Medication will be injected into SI joint under ultrasound guidance

Treatment groups

20 Participants
are divided into 2 treatment groups
Group A: CorticosteroidActive comparator 1 intervention
Group B: KetorolacActive comparator 1 intervention

Trial outcomes

Primary outcomes

1

Sacroiliac (SI) joint pain

SI joint pain at 2, 6 and 12 week marks post SI joint injection measured on visual analogue scale. Higher numbers equate to worse pain and worse outcomes.

Time frame
3 months following SI joint injection

Secondary outcomes

Other outcomes

Sponsors and contacts

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