LED Therapy for Third Molar Surgery
Trial statusNot yet recruiting
Trial phaseEarly Phase 1
Trial typeInterventional
Biological sexAll
Age20-55
SponsorHuashan Hospital
About this trial
LED Therapy for third molar surgery
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Healthy Asians;
20-55 years old;
Having mandibular third molars that are inappropriately erupted and need to be extracted due to caries, orthodontic reasons and/or periodontal disease;
Disqualifiers
Underlying diseases: diabetes, cardiovascular disease, coagulation disorder, osteoporosis, hypertension, neurological disease, psychological disorder, tumor, systemic infection or cyst at the extraction site;
Women who are preparing for pregnancy, pregnant or breastfeeding;
Medication history: use of analgesics, anti-inflammatory drugs and/or antibacterial drugs 2 weeks before tooth extraction, need for systemic medication other than acetaminophen after surgery, allergy to acetaminophen, use of anticoagulants, bisphosphonates;
Bad habits, such as addicted to smoking, drinking, etc.;
Trial design
Design model
Parallel
Treatments tested in this trial
photobiomodulation
Device830 nm LED was used to irradiate the post-extraction area
Antibiotic
Drugibuprofen 0.3 g bid for 3 days, metronidazole 0.1 g tid, and cefaclor 0.375 g bid for 7 days after surgery
Treatment groups
50 Participants
are divided into 2 treatment groupsGroup A: Control GroupSham comparator 1 intervention
Group B: Treatment GroupExperimental treatment 2 interventions
Trial outcomes
Primary outcomes
1
Pain
Visual Analogue Scale，VAS
Time frame
Day 72
Swelling
Facial swelling was measured in 2 planes: the distance between the tragus and lip commissure and the distance between the gonion and external canthus of the eye.
Time frame
Day 3; Day 73
Trismus
Trismus was evaluated by measuring the maximum mouth opening between the edges of the upper and lower central incisors with a calibrated ruler.
Time frame
Day 3; Day 7Secondary outcomes
1
Quality of life score
OHIP-14 Scale
Time frame
Day 3; Day 7Sponsors and contacts
Click on the lead sponsor to view all of their trials.
Source ClinicalTrials.gov
This trial is not recruiting at the moment. You can still explore other options: