An examination of the participants mouth is done first. If they do not have enough bone to place a dental implant as a tooth replacement, and they have chosen sinus augmentation to treat this issue during implant placement a leukocyte platelet rich fibrin (L-PRF) will be performed instead of using other available options. The only difference from usual care is that L-PRF alone will be used as the bone formation material and two additional x-rays, Cone Beam Computed Tomography (CBCTs) will be taken right after the procedure and then again six months after treatment. CBCT is a special type of 3D X-ray commonly used in dentistry and oral surgery. Unlike traditional X-rays, which create flat 2D images, CBCT produces detailed 3D images of your teeth, jawbone, nerves, and nearby tissues.
Ability of participant to understand and the willingness to sign a written informed consent document.
English speaking.
Individuals who are normal healthy or have a diabetes diagnosis with a current HbA1c < 7.0.
Partially edentulous patients (18-85 years of age) requiring maxillary sinus augmentation for dental implant placement
Maxillary sinus disease
Diabetes diagnosis with a current HbA1c > 7.1 or greater, or if HbA1c status cannot be confirmed, due to diabetes effect on bone metabolism
Pregnant or attempting to become pregnant
Having a disease that affects bone metabolism
Single group
Leukocyte Platelet Rich Fibrin
Biological/VaccineL-PRF does not directly induce bone formation within the maxillary sinus; rather, it serves as an autologous biologic scaffold that facilitates the regenerative process
Maxillary Sinus Volume using 2D imaging
Regular x-rays are used to take measurements
Maxillary Sinus Volume using 3D imaging
3D CBCT images are used for measurements
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This trial is not recruiting at the moment. You can still explore other options:
