Eating Behavior, Nutritional Status and Appetite Hormones After Bariatric Surgery
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-50
SponsorÖzlem ÖZPAK AKKUŞ
About this trial
This study aims to evaluate changes in eating behavior attitudes, nutritional status, and appetite-regulating hormonal parameters in individuals who have undergone Laparoscopic Sleeve Gastrectomy (LSG). The study will be conducted at Bursa Yıldırım Doruk Hospital, Department of General Surgery. A total of 40 volunteer participants who underwent LSG within the last month will be included. Participants will be assessed at baseline (shortly after surgery) and at 6-month follow-up. Assessments will include anthropometric measurements (body weight, height, waist and hip circumference, BMI, waist-to-hip ratio), 3-day dietary intake records analyzed using BeBIS 8.2 software, and the Adult Eating Behavior Scale. Biochemical parameters including fasting blood glucose, total cholesterol, triglycerides, HDL, LDL, VLDL cholesterol, and insulin will be obtained from patient files and analyzed using Advia Chemistry 2400 and Advia XPT devices. Additionally, appetite-regulating hormones (ghrelin, GLP-1, PYY) will be analyzed from residual blood samples using the ELISA method with RelAssay Diagnostics kits by Teknogen Bioengineering Laboratory. All data will be compared between baseline and 6-month follow-up to evaluate the impact of bariatric surgery on nutritional and hormonal outcomes.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Having undergone Laparoscopic Sleeve Gastrectomy (LSG) within the last month
Aged between 18-50 years
Signing the informed consent form
Having a Body Mass Index (BMI) of 40 kg/m2 or between 35-40 kg/m2 with obesity-related comorbidities
Disqualifiers
Not having undergone Laparoscopic Sleeve Gastrectomy (LSG) or not planning to undergo bariatric surgery
Not being in the age range of 18-50 years
Not signing the informed consent form
Having a Body Mass Index (BMI) greater than 40 kg/m2 or less than 35 kg/m2 without obesity-related comorbidities
Trial population
Adult patients who underwent Laparoscopic Sleeve Gastrectomy (LSG) within the last month at Bursa Yıldırım Doruk Hospital, General Surgery Clinic, under the supervision of Assoc. Prof. Dogukan Durak, and who meet the inclusion and exclusion criteria.
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
Anthropometric Measurements and Dietary Assessment
Other interventionAnthropometric measurements (body weight, height, waist and hip circumference, BMI, waist-to-hip ratio), 3-day dietary intake records, Adult Eating Behavior Scale, and biochemical and hormonal parameters (fasting blood glucose, lipid profile, insulin, ghrelin, GLP-1, PYY) will be assessed at baseline and at 6-month follow-up.
Treatment groups
40 Participants
are divided into 1 treatment groupGroup A: LSG Patients1 intervention
Trial outcomes
Primary outcomes
1
Change in Serum Ghrelin Concentration (pg/mL)
Change in serum ghrelin levels between baseline and 6-month follow-up, assessed by ELISA method.
Time frame
Baseline and 6 months after surgery2
Change in Serum GLP-1 Concentration (pmol/L)
Change in serum glucagon-like peptide-1 (GLP-1) levels between baseline and 6-month follow-up, assessed by ELISA method.
Time frame
Baseline and 6 months after surgery3
Change in Serum PYY Concentration (pg/mL)
Change in serum peptide YY (PYY) levels between baseline and 6-month follow-up, assessed by ELISA method.
Time frame
Baseline and 6 months after surgery4
Change in Adult Eating Behavior Scale Total Score (0-100)
Change in Adult Eating Behavior Scale total score between baseline and 6-month follow-up. Scale is scored between 0-100; higher scores indicate more positive eating behavior attitudes.
Time frame
Baseline and 6 months after surgerySecondary outcomes
1
Change in Body Weight (kg)
Change in body weight between baseline and 6-month follow-up.
Time frame
Baseline and 6 months after surgery2
Change in Body Mass Index (kg/m²)
Change in BMI between baseline and 6-month follow-up. Weight and height will be combined to report BMI in kg/m².
Time frame
Baseline and 6 months after surgery3
Change in Waist Circumference (cm)
Change in waist circumference between baseline and 6-month follow-up.
Time frame
Baseline and 6 months after surgery4
Change in Hip Circumference (cm)
Change in hip circumference between baseline and 6-month follow-up.
Time frame
Baseline and 6 months after surgerySponsors and contacts
Click on the lead sponsor to view all of their trials.
Özlem ÖZPAK AKKUŞ
Lead sponsor
Toros University
Sponsor institution
Source ClinicalTrials.gov
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