Eccentric Exercise and Fatigue in Multiple Sclerosis
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-75
SponsorHunter College of City University of New York
About this trial
The goal of this observational study is to compare the impact of eccentric resistance training to traditional resistance training on fatigue in persons with multiple sclerosis (MS). The primary question this study is asking is the following: is eccentric resistance training more fatiguing than traditional resistance training in persons with MS?. Participants will be asked to come for two sessions for two weeks. In the first week, subjects will undergo a bout of either traditional or eccentric resistance training. The next day they will return to assess their level of fatigue. The following week the subject will return and undergo whatever type of training they did not experience the first week, and it's effects on fatigue will again be assessed. The difference between the subjects level of fatigue for either condition will be compared.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Definitive diagnosis of Multiple Sclerosis.
Ability to walk for 6 minutes continuously with or without assistive device
Ability read, understand and sign and informed consent
Disqualifiers
Evidence of recent exacerbation in the last 2 months prior to starting the study
Orthopedic, cardiopulmonary, or non -MS neurologic condition that could interfere with carrying out the study protocol
Trial population
Ambulatory persons with MS
Trial design
Design model
Case-crossover
Time perspective
Retrospective
Treatments tested in this trial
Resistance training
BehavioralEccentric resistance training and tradional resistance training
Treatment groups
30 Participants
are divided into 1 treatment groupGroup A: Persons with Multiple sclerosis1 intervention
Trial outcomes
Primary outcomes
1
6-Minute walk test
Subject walks at best possible pace with or without assistive device for 6 minutes. Total distance walked as well as distance per minute is measured
Time frame
Pre-intervention and post intervention for each condition (eccentric and traditional strength training). There is a 36-48 hour period between the pre-intervention and post intervention for each conditionSecondary outcomes
1
Visual analog scale of fatigue
Immediately before and after each 6 minute walk subjects will make a mark on a 100mm line indicating their level of fatigue
Time frame
Pre-intervention and post-intervention for each condition (eccentric vs traditional strength training). There is a 36-48 hour period between the pre-intervention and post intervention for each conditionSponsors and contacts
Click on the lead sponsor to view all of their trials.
Hunter College of City University of New York
Lead sponsor
City University of New York, School of Public Health
Sponsor institution
Source ClinicalTrials.gov