Eccentric Exercise With Blood Flow Restriction vs Resistance Training for Lateral Epicondylitis
ConditionLateral Epicondylitis
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age25-45
SponsorNimra Rafiq
About this trial
This randomized controlled trial aims to compare the effectiveness of eccentric training combined with blood flow restriction (ECC+BFR) versus heavy slow resistance (HSR) training in patients with chronic lateral epicondylitis. The study will recruit 40 participants (accounting for 10% attrition), aged 25-45 years, from Sakina Memorial Hospital Sheikhupura and University of Lahore Teaching Hospital using convenience sampling. Participants will be randomly allocated into two groups: an interventional group receiving ECC+BFR and a control group undergoing HSR training. Both interventions will be administered three times per week for 8 weeks under professional supervision. Outcome measures including pain intensity (NPRS), patient-specific functional performance (PSFS), muscle strength, and hypertrophy will be assessed at baseline, 4 weeks, and 8 weeks. Data will be analyzed using SPSS, with appropriate parametric or non-parametric tests applied after checking data normality. Ethical approval will be obtained, informed consent will be secured, and participant confidentiality will be strictly maintained.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
None
Disqualifiers
None
Trial design
Design model
Parallel
Treatments tested in this trial
interventional group A
BehavioralThe interventional group will receive eccentric wrist extensor exercises combined with blood flow restriction therapy, using a pneumatic cuff inflated to 50-60% limb occlusion pressure. Exercises will be performed at 20-30% 1-RM using a 30-15-15-15 repetition protocol, emphasizing slow controlled eccentric contractions. Sessions will be conducted three times weekly for 8 weeks, totaling 24 supervised sessions.
control group b
BehavioralThe control group will undergo a heavy slow resistance training protocol, involving wrist extensor exercises performed at 70-85% of 1-RM, with slow concentric and eccentric phases (3 seconds each). Participants will complete 3-4 sets of 6-8 repetitions, with adequate rest intervals, following the same session frequency and duration as the intervention group.
Treatment groups
40 Participants
are divided into 2 treatment groupsGroup A: interventional group AExperimental treatment 1 intervention
Group B: Control group BActive comparator 1 intervention
Trial outcomes
Primary outcomes
1
Pain Intensity (Numeric Pain Rating Scale)
Pain intensity will be assessed using the Numeric Pain Rating Scale (NPRS), a validated 11-point scale ranging from 0 (no pain) to 10 (worst imaginable pain). Participants will rate their average elbow pain during daily activities involving the affected upper limb.
Time frame
Baseline, 4 weeks, and 8 weeksSecondary outcomes
1
Patient-Specific Functional Performance (PSFS)
Functional performance will be assessed using the Patient-Specific Functional Scale (PSFS). Participants will identify activities affected by lateral epicondylitis and rate their ability to perform each activity on an 11-point scale ranging from 0 (unable to perform) to 10 (able to perform at pre-injury level). Higher scores indicate improved functional ability.
Time frame
Baseline, 4 weeks, and 8 weeksSponsors and contacts
Click on the lead sponsor to view all of their trials.
Nimra Rafiq
Lead sponsor
University of Lahore
Sponsor institution
Source ClinicalTrials.gov