EEG Changes and Cognitive Profiles in Sepsis Patients With Different Inflammatory Phenotypes

ConditionsSepsis Sepsis Associated Encephalopathy Sepsis and Septic Shock Sepsis at Intensive Care Unit

Trial statusNot yet recruiting

Trial phaseNot listed

Trial typeObservational

Biological sexAll

Age18-90

SponsorXiangya Hospital of Central South University

About this trial

To characterize the electroencephalogram (EEG) features of sepsis patients with distinct inflammatory response phenotypes, dynamically track their evolutionary trajectories, and analyze their associations with long-term changes in cognitive function.

Eligibility criteria

Qualifiers

Age ≥18 years and ≤90 years

First-time admission to the Intensive Care Unit (ICU)

Diagnosis of sepsis according to Sepsis-3.0 criteria (documented or clinically suspected infection plus Sequential Organ Failure Assessment [SOFA] score ≥2 points)

Expected ICU survival time ≥24 hours

Disqualifiers

Pregnancy or lactation

Cardiopulmonary-cerebral resuscitation (CPCR) performed during the current hospital admission

Trial design

Treatments tested in this trial

EEG monitoring

Treatment groups

78 Participants

are divided into 2 treatment groups

Sponsors and collaborators

Xiangya Hospital of Central South University

Lead sponsor

Source ClinicalTrials.gov