EEG-Guided Cognitive Function Preservation in Patients With Brain Tumors
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-75
SponsorBo Wang
About this trial
Brain tumors and their surgical treatment may impair cognitive function, affecting patients' quality of life. This prospective single-arm study aims to evaluate the feasibility and clinical utility of an EEG-based neural signal decoding strategy for cognitive function preservation in patients undergoing brain tumor surgery. Participants will undergo standardized neuropsychological assessments together with preoperative, intraoperative, and postoperative electrophysiological recordings. The study will investigate whether EEG-based neural decoding can improve objective cognitive function assessment and support individualized functional preservation during brain tumor surgery.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Age 18 years to 75 years.
Patients diagnosed with brain glioma and scheduled for surgical treatment.
Conscious and able to understand study procedures.
Able to complete neuropsychological assessments.
Disqualifiers
Severe dysfunction of major organs (heart, lung, liver, or kidney).
Severe psychiatric disorders or cognitive impairment.
Severe language impairment preventing completion of study procedures.
Any other condition judged by the investigator to make participation inappropriate.
Trial design
Design model
Single group
Treatments tested in this trial
EEG-Based Neural Signal Decoding Strategy
Procedure/SurgeryEEG-based neural signal decoding will be performed during the perioperative period to identify cognitive functional networks and assist individualized cognitive function preservation during brain tumor surgery.
Treatment groups
10 Participants
are divided into 1 treatment groupGroup A: EEG-Guided Cognitive Function PreservationExperimental treatment 1 intervention
Trial outcomes
Primary outcomes
1
Mini-Mental State Examination (MMSE) Total Score
Cognitive function assessed using the Mini-Mental State Examination (MMSE). The total score ranges from 0 to 30, with higher scores indicate better cognitive function.
Time frame
Baseline, postoperative 1 week, postoperative 1 month, and postoperative 3 months2
Montreal Cognitive Assessment (MoCA) Total Score
Cognitive function assessed using the Montreal Cognitive Assessment (MoCA). The total score ranges from 0 to 30, with higher scores indicate better cognitive function.
Time frame
Baseline, postoperative 1 week, postoperative 1 month, and postoperative 3 monthsSponsors and contacts
Click on the lead sponsor to view all of their trials.
Bo Wang
Lead sponsor
Huanhu Hospital Affiliated to Tianjin Medical University
Sponsor institution
Source ClinicalTrials.gov
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