EEG Measurements to Capture DBS-induced Electric Potentials
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age35-85
SponsorUniversitätsklinikum Hamburg-Eppendorf
About this trial
To measure the electric fields induced by DBS (deep brain stimulation) on the scalp and to improve electric field simulations, the investigators will measure EEG (electroencephalography) measurements with high sampling rates (\>100 kHz). The investigators hypothesize that we can improve electric field simulations of DBS by validating and calibrating the simulations based on EEG measurements at high sampling rates (\>100 kHz).
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Provision of written informed consent by the patient
Age 35 - 85
patient groups: Parkinson's disease, essential tremor, dystonia
>3 months after surgery for DBS
Disqualifiers
None
Trial population
Patients implanted with deep brain stimulation
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
EEG recording
Other interventionEEG will be recorded at high sampling rate
Treatment groups
20 Participants
are divided into 1 treatment groupGroup A: EEG measurement during DBS1 intervention
Trial outcomes
Primary outcomes
1
Electric potential at the EEG locations
The investigators will extract the DBS pulses from the EEG data and check the distribution of the electric potentials as seen in simulations based on individual MRI and CT images. Parameters of the simulation pipeline (e.g. conductances) will be adjusted so that the simulation models fit the data.
Time frame
during DBSSponsors and contacts
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Universitätsklinikum Hamburg-Eppendorf
Lead sponsor
University of Twente
Collaborator
Source ClinicalTrials.gov