About this trial
The main aim of this study is to understand if chronic supplementation (12 weeks) of a milk fat globule membrane containing supplement, called bioactive whey protein concentrate, improves human muscle function greater than a placebo supplement within a cohort of healthy, recreationally active adults. Furthermore, we aim to investigate whether any potential benefits of milk fat globule membrane are influenced by age through the assessment of 2 distinct age subgroups (young and older). We hypothesise that neuromuscular function (strength and power) will increase from pre to post within the group that consumes bioactive whey protein concentrate but not the placebo group, with a greater increase in the older group compared to the young group.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
18-30 or 60-75 years old
Male or female
Healthy with no contraindications to exercise
Classified as recreationally active (meet the government's guidelines for weekly physical activity - 150 minutes of moderate physical activity or 75 minutes of vigorous physical activity)
Disqualifiers
Any injury, medical condition or symptom precluding the ability to complete strenuous exercise as identified by the health screen questionnaire and physical activity readiness questionnaire
Uncontrolled hypertension (blood pressure of 140/90 mmHg or higher) as identified by recording resting blood pressure
Neuromuscular or musculoskeletal disease
Occurrence of a severe injury to the lower limbs or back within the previous 6 months (time loss of > 21 days of normal activity)
Trial design
Parallel
Treatments tested in this trial
Bioactive whey protein concentrate
Dietary supplementEvery day for 12 weeks, participants will mix 1 scoop of supplement with \~350ml of water and consume the resultant drink alongside their breakfast.
Whey protein isolate supplement
Dietary supplementEvery day for 12 weeks, participants will mix 1 scoop of supplement with \~350ml of water and consume the resultant drink alongside their breakfast.
Treatment groups
Trial outcomes
Primary outcomes
Maximal voluntary isometric torque of the knee extensors
Assessed during maximal voluntary contractions (Nm)
Secondary outcomes
Rate of torque development of the knee extensors
Assessed during explosive isometric contractions (Nm/s)
Peak twitch torque (knee extensors)
(Nm)
Time to peak twitch torque (knee extensors)
(ms)
Half-relaxation time during twitch contractions (knee extensors)
(ms)
Sponsors and contacts
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Loughborough University
Lead sponsor
Volac International Limited
Collaborator