To conduct a multi-center, randomized, controlled clinical study aimed at formally evaluating the impact of pressing therapy on the success rate in patients with recurrent implantation failure.
Meets the criteria for RIF diagnosis (≥ 2 instances of unsuccessful transfer of high-quality embryos).
Age: 20 to 40 years old.
Planning for a cycle involving the transfer of frozen-thawed embryos (FET).
Possession of a transplantable D3 frozen embryo (≥6 cells) or a frozen blastocyst (≥3BC).
Individuals planning to undergo preimplantation genetic diagnosis (PGD).
Recipients of egg donations.
Chromosomal abnormalities in either spouse or one partner (excluding chromosomal polymorphisms).
Patients with known embryo-related factors leading to implantation failure.
Parallel
Placebo Group
Devicenonpenetrating placebo needles
Acupuncture group
Deviceindwelling intradermal needles
clinical pregnancy
defined as ultrasonographic detection of an intrauterine gestational sac following embryo transfer
β-hCG-positive pregnancy
defined as serum β-hCG concentration \>10 mIU/mL on day 14 post-transfer
Endometrial thickness
Endometrial thickness on Transformation Day
endometrial blood flow
anxiety assessment
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This trial is not recruiting at the moment. You can still explore other options:
