Effects of Agent-assisted, LLM-assisted and Traditional Workflows on Diagnosis and Management Planning at Admission

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorSecond Affiliated Hospital, Zhejiang University, School of Medicine

About this trial

The goal of this clinical trial is to evaluate whether AI-assisted workflows improve physicians' admission diagnosis and management planning performance on standardized simulated inpatient cases, among practicing internal medicine and surgery physicians across all seniority levels and across three tiers of the Chinese healthcare system.

The main questions it aims to answer are:

* Does the Agent-assisted workflow yield better structured admission diagnosis and management planning scores than standalone LLM assistance? * Does the Agent-assisted workflow outperform the traditional workflow without AI tools? Researchers will compare three parallel groups (traditional workflow group, LLM-assisted group, Agent-assisted group) to determine whether the Agent tool can improve diagnostic accuracy and efficiency.

Participants will:

* Be recruited from 15 hospitals in China and participate remotely under video proctoring * Be randomly assigned to one of the three fixed workflows, with randomization stratified by hospital tier, specialty and seniority * Complete 6 anonymized simulated HIS admission cases within one hour * Submit structured answers for each case covering principal diagnosis, secondary diagnoses, differential diagnoses, diagnostic justification, next diagnostic or therapeutic steps, consultation and referral decisions, and diagnostic confidence * Have their operation logs and time consumption recorded automatically by the study platform

Eligibility criteria

Qualifiers

Hold a Medical Practitioner Qualification Certificate and/or Medical License, or be a recognized standardized resident physician; able to independently read electronic medical records, laboratory and imaging reports on an HIS.

Currently engaged in clinical work in internal medicine or surgery at one of the 15 participating hospitals.

Able to complete the case assessment in one continuous hour without breaks.

Able to participate remotely under video proctoring, with a stable internet connection and a working camera.

Disqualifiers

Have previously accessed the official test cases or reference standard of this study.

Unable to complete the training module, qualification test, or all experimental tasks.

Have conflicts of interest, e.g. participation in developing core algorithms of the tested system.

Unwilling to comply with remote proctoring, including keeping the camera on throughout.

Trial design

Treatments tested in this trial

  • Agent-assisted workflow
  • LLM-assisted workflow
  • Traditional Workflow

Treatment groups

180 Participants
are divided into 3 treatment groups

Sponsors and collaborators