A single-center, prospective cohort trial aims to provide stronger evidence regarding the impact of degenerative spondylolisthesis on the clinical outcome of unilateral biportal endoscopy for lumbar spinal stenosis
Age range: 50-80 years
Diagnosis of LSS affecting 1-2 vertebral levels
Predominant manifestation of neurogenic intermittent claudication, with ineffective conservative treatment for at least 3 months
Presence of lumbar DS of less than grade II and absence of spine instability
Diagnosis of isthmic lumbar spondylolisthesis or lumbar DS of grade ≥II
Evidence of instability at the affected vertebral level (intervertebral angle change > 15° and/or vertebral translation ≥ 4.5 mm in standing flexion-extension radiographs of the lumbar spine)
History of prior surgery at the affected vertebral level
Presence of scoliosis with a Cobb angle >20º
Eligible patients with LSS who are scheduled to undergo UBE-based decompression, performed by an experienced spine surgeon at Beijing Friendship Hospital, will be recruited from the outpatient clinic for this study.
Cohort
Prospective
Not listed
Oswestry Disability Index (ODI)
0-100%, the higher the score, the more severe the lumbar spine dysfunction
X-ray
Progression of lumbar spondylolisthesis, assessed by postoperative lumbar radiography; (2) Measurement of sagittal translation, segmental angulation, and posterior opening based on postoperative standing flexion-extension radiographs
Computed tomography (CT) scan
Assessment of bone resection area and preservation rate of the facet joint using postoperative computed tomography (CT) scans
Magnetic resonance imaging (MRI)
Calculation of the enlargement ratio of the dural sac based on postoperative magnetic resonance imaging (MRI)
Surgical complication
Any adverse events will be recorded to evaluate the safety of decompression using UBE for LSS with or without DS
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