Effect of Epidural Analgesia on Regional Lung Ventilation in Parturient Women as Assessed by Thoracic Impedance

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexFemale
AgeNot listed
SponsorErasme University Hospital

About this trial

The goal of this observational study is to learn more about the effect of obstetric epidural anesthesia on regional lung ventilation in healthy parturient women. The main question it aims to answer is whether the initiation or epidural analgesia improves or not regional lung ventilation in healthy women at term during labor.

Participants will be subject to measurements of pulmonary impedance by electric impedance tomography before and after the start of epidural analgesia. No change will be applied to clinical care as a result of this measurement.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

At-term pregnancy (at least 36 weeks)

ASA class I-II

Disqualifiers

American Society of Anesthesiologists (ASA) Class III or more

BMI>35 before pregnancy

Contraindication to routinely administrated drugs (levobupivacaine, lidocaine, sufentanil)

Contraindication to epidural analgesia

Trial population

The study will include healthy pregnant patients that come for spontaneous or induced labor at the hospital's delivery room.

Trial design

Design model

Case-only

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

100 Participants
are grouped into 1 trial group
Group A: Observational cohort

Trial outcomes

Primary outcomes

1

Regional lung ventilation (ROI 1-4)

Assess regional ventilation as measured by electric impedance in each of the 4 Regions Of Interest (from anterior to posterior) in which the lung is divided, before and after epidural analgesia

Time frame
"before" measurements will be taken just before applying lumbar epidural analgesia, and "after" measurements will be taken 5 minutes and ten minutes after starting lumbar epidural analgesia. Measurements take 10 minutes of continuous registration

Secondary outcomes

Other outcomes

Sponsors and contacts

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This trial is not recruiting at the moment. You can still explore other options: