Effect of Epidural Catheter Retention Depth on Labor Analgesia Performed in DPE Combined With PIEB Model

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age18-45
SponsorGeneral Hospital of Ningxia Medical University

About this trial

The purpose of this study is to observe the appropriate indwelling depth of epidural catheter when labor analgesia is performed in the mode of DPE combined with PIEB, and then shorten the onset time of labor analgesia and reduce the occurrence of catheter-related adverse outcomes.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Those aged 18 to 45 years old;

Pregnancy lasts for 37 to 42 weeks;

Single healthy pregnant women with cervical dilation < 3.0 cm who wish to use epidural labor analgesia;

The NRS score of uterine contraction pain is > 3;

Disqualifiers

Those with contraindications to intraspinal anesthesia;

Those with a history of allergy to local anesthetics and opioids;

Pregnancy diseases (such as pregnancy-induced hypertension, preeclampsia or gestational diabetes, etc.);

Known fetal abnormalities or situations associated with an increased risk of cesarean section;

Trial design

Design model

Single group

Treatments tested in this trial

  • The indwelling length of epidural catheter is 3 centimeters.

    Procedure/Surgery

    When performing Dural Puncture Epidural technique with Programmed Intermittent Epidural Bolus(PIEB) mode for labor analgesia, According to different indwelling lengths of epidural catheters as variables, patients are divided into three treatment groups(3cm group 、5cm group and 7cm group)

  • The indwelling length of epidural catheter is 5 centimeters.

    Procedure/Surgery

    When performing Dural Puncture Epidural technique with Programmed Intermittent Epidural Bolus(PIEB) mode for labor analgesia, According to different indwelling lengths of epidural catheters as variables, patients are divided into three treatment groups(3cm group 、5cm group and 7cm group)

  • The indwelling length of epidural catheter is 7 centimeters.

    Procedure/Surgery

    When performing Dural Puncture Epidural technique with Programmed Intermittent Epidural Bolus(PIEB) mode for labor analgesia, According to different indwelling lengths of epidural catheters as variables, patients are divided into three treatment groups(3cm group 、5cm group and 7cm group)

Treatment groups

102 Participants
are divided into 3 treatment groups
Group A: 3cm groupOther 1 intervention
Group B: 5cm groupOther 1 intervention
Group C: 7cm groupOther 1 intervention

Trial outcomes

Primary outcomes

1

Time of satisfactory analgesia.

The time when the NRS score is less than 3 after the first administration during labor analgesia with DPE combined with PIEB mode.

Time frame
First dose in the epidural space to NRS score being less than 3.
2

Consumption of ropivacaine per unit time.

The consumption of ropivacaine per unit time during the entire labor analgesia process.

Time frame
First dose in the epidural space to the end of the third stage of labor.

Secondary outcomes

1

Related adverse outcomes.

Occurrence of epidural catheter prolapse, itching, nausea, vomiting, hypotension and unilateral block.

Time frame
First dose in the epidural space to the end of the third stage of labor.
2

Anesthesia level and lower limb motor block.

Use the needle prick method to measure the anesthesia level and lower limb motor block after satisfactory labor analgesia.

Time frame
When labor analgesia is satisfactory.
3

Duration of labor.

Duration of the first, second, and third stages of labor.

Time frame
From the onset of labor to its end.
4

Changes in fetal heart rate and uterine contraction pressure.

Observe the changes in fetal heart rate and uterine contraction pressure before and after labor pain.

Time frame
Before and after labor pain.

Other outcomes

Sponsors and contacts

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