About this trial
The purpose of this study is to observe the appropriate indwelling depth of epidural catheter when labor analgesia is performed in the mode of DPE combined with PIEB, and then shorten the onset time of labor analgesia and reduce the occurrence of catheter-related adverse outcomes.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Those aged 18 to 45 years old;
Pregnancy lasts for 37 to 42 weeks;
Single healthy pregnant women with cervical dilation < 3.0 cm who wish to use epidural labor analgesia;
The NRS score of uterine contraction pain is > 3;
Disqualifiers
Those with contraindications to intraspinal anesthesia;
Those with a history of allergy to local anesthetics and opioids;
Pregnancy diseases (such as pregnancy-induced hypertension, preeclampsia or gestational diabetes, etc.);
Known fetal abnormalities or situations associated with an increased risk of cesarean section;
Trial design
Single group
Treatments tested in this trial
The indwelling length of epidural catheter is 3 centimeters.
Procedure/SurgeryWhen performing Dural Puncture Epidural technique with Programmed Intermittent Epidural Bolus(PIEB) mode for labor analgesia, According to different indwelling lengths of epidural catheters as variables, patients are divided into three treatment groups(3cm group 、5cm group and 7cm group)
The indwelling length of epidural catheter is 5 centimeters.
Procedure/SurgeryWhen performing Dural Puncture Epidural technique with Programmed Intermittent Epidural Bolus(PIEB) mode for labor analgesia, According to different indwelling lengths of epidural catheters as variables, patients are divided into three treatment groups(3cm group 、5cm group and 7cm group)
The indwelling length of epidural catheter is 7 centimeters.
Procedure/SurgeryWhen performing Dural Puncture Epidural technique with Programmed Intermittent Epidural Bolus(PIEB) mode for labor analgesia, According to different indwelling lengths of epidural catheters as variables, patients are divided into three treatment groups(3cm group 、5cm group and 7cm group)
Treatment groups
Trial outcomes
Primary outcomes
Time of satisfactory analgesia.
The time when the NRS score is less than 3 after the first administration during labor analgesia with DPE combined with PIEB mode.
Consumption of ropivacaine per unit time.
The consumption of ropivacaine per unit time during the entire labor analgesia process.
Secondary outcomes
Related adverse outcomes.
Occurrence of epidural catheter prolapse, itching, nausea, vomiting, hypotension and unilateral block.
Anesthesia level and lower limb motor block.
Use the needle prick method to measure the anesthesia level and lower limb motor block after satisfactory labor analgesia.
Duration of labor.
Duration of the first, second, and third stages of labor.
Changes in fetal heart rate and uterine contraction pressure.
Observe the changes in fetal heart rate and uterine contraction pressure before and after labor pain.
Sponsors and contacts
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