Effect of Erector Spinae (ESP) Block on Opioid Reduction and Enhanced Recovery After Posterior Cervical Spine Surgery

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-80
SponsorUniversity Health Network, Toronto

About this trial

Patients undergoing spine surgery frequently experience significant pain after surgery. This can limit patient activity and hinder rehabilitation. If inadequately treated, severe pain can result in emotional and psychological distress and ultimately impact long-term function, and increase the risk of developing pain that lasts longer than six months associated with depression, anxiety and disability.

More specifically, Erector Spinae Plane (ESP) block is a recently described plane block designed to block the dorsal and ventral rami of the thoracic spinal nerves. It has shown to be an effective modality for postoperative pain management as a part of multimodal analgesia in spinal surgery.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

None

Disqualifiers

In patients who are allergic to local anesthetics.

ASA IV patients

Lack of informed consent

Pregnant patient.

Trial design

Design model

Parallel

Treatments tested in this trial

  • Erector Spinae (ESP) Block with Lidocaine/Bupivacaine

    Drug

    Bilateral ESP block at T1 level with 20 ml of 1:1 mixture (2% Lidocaine: 0.5% bupivacaine)

  • Erector Spinae (ESP) Block with placebo

    Drug

    Bilateral ESP block at T1 level with 20 ml of 0.9% normal saline

Treatment groups

52 Participants
are divided into 2 treatment groups
Group A: Study groupExperimental treatment 1 intervention
Group B: Placebo GroupPlacebo comparator 1 intervention

Trial outcomes

Primary outcomes

1

Quality of Recovery 40 Questionnaire

the global Quality of Recovery-40 aggregate score is a scale from (1 to 5, where: 1 = very poor and 5 = excellent)

Time frame
24 hours after surgery.

Secondary outcomes

1

Postoperative pain

is a visual analog scale from (1 to 10, where: 1 is the mildest and 10 the worst possible)

Time frame
2 weeks and one month
2

Opioids consumption

Patient Opioid/Non-Opioid Pain Medications Diary Card After Surgery

Time frame
2 weeks and one month

Other outcomes

Sponsors and contacts

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