Health TrialsbyHealthPanel

Effect of High-Flow Nasal Oxygen on Laryngoscopic View

ConditionsHigh Flow Nasal CanulaLaryngoscopyAirway AnesthesiaAirway Complication of AnaesthesiaDifficult AirwayDifficult / Failed Intubation
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorMasarykova Nemocnice v Usti nad Labem, Krajska Zdravotni a.s.

About this trial

This prospective, multicenter observational study aims to evaluate the effect of different flow rates of high-flow nasal oxygen (HFNO) on the quality of the laryngoscopic view during videolaryngoscopy in adult patients undergoing general anesthesia. Each patient will serve as their own control, with repeated measurements obtained at three different HFNO flow settings (0, 40, and 60 L/min). The study will assess objective and subjective parameters of glottic visualization using standardized scoring systems.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Age ≥18 years

Scheduled for endotracheal intubation under general anesthesia

Use of videolaryngoscopy

Disqualifiers

Anticipated difficult airway

Emergency intubation

Contraindications to HFNO

Inability to obtain adequate video recording

Trial population

Adult patients undergoing elective surgical procedures requiring endotracheal intubation under general anesthesia.

Trial design

Design model

Case-control

Time perspective

Prospective

Treatments tested in this trial

  • HFNO flow 0

    Device

    Different flows will be applied to patients undergoing general anaesthesia during airway management. In this arm flow will be 0 l/min. During these flows images will be captured using videolaryngoscope.

  • HFNO flow 40

    Device

    Different flows will be applied to patients undergoing general anaesthesia during airway management. In this arm flow will 40 l/min. During these flows images will be captured using videolaryngoscope.

  • HFNO 60

    Device

    Different flows will be applied to patients undergoing general anaesthesia during airway management. In this arm flow will 60 l/min. During these flows images will be captured using videolaryngoscope.

Treatment groups

150 Participants
are divided into 1 treatment group
Group A: Group HFNO3 interventions

Trial outcomes

Primary outcomes

1

Quality of view

Percentage of glottic opening (POGO score) assessed from recorded videolaryngoscopic images.

Time frame
From induction of general anesthesia to completion of orotracheal intubation (not longer than 10 minutes).

Secondary outcomes

1

Cormack-Lehane classification

Ordinal grading of glottic view using Cormack- Lehane classification.

Time frame
From induction of general anesthesia to completion of orotracheal intubation (not longer than 10 minutes).
2

Subjective image quality (Likert scale)

Subjective assessment of laryngoscopic image quality rated on a 5-point Likert scale (1 = very poor, 5 = excellent) by independent evaluators blinded to HFNO flow conditions

Time frame
From induction of general anesthesia to completion of orotracheal intubation (not longer than 10 minutes).

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Masarykova Nemocnice v Usti nad Labem, Krajska Zdravotni a.s.

Lead sponsor

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: