About this trial
Fascial plane blocks are traditionally considered regional anesthesia techniques, where a mixture of local anesthetic (LA) is injected into a plane between two fascial layers, with the aim of spreading along this anatomical plane to block the nerves lying within or passing through it . Various pathophysiological processes that alter the structure and characteristics of fasciae can affect the spread of the local anesthetic and the success of the block. Diabetes, hormonal changes, and cannabinoid use are among these factors. This study aims to investigate the effects of hormonal changes during the menstrual cycle on subcostal TAP block.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
ASA I-II, female, Laparoscopic cholecyctectomy, Subcostal TAP , 18-65 years old patient
Disqualifiers
ASA III-IV
<18 , >65 years old patients
menstrual disorders
Trial design
Parallel
Treatments tested in this trial
Subcostal Transversus Abdominis Plane Block
Other interventionAfter ensuring airway safety under general anesthesia, a bilateral Transversus Abdominis Plane Block using 20 cc of 0.25% bupivacaine with a subcostal approach under ultrasound guidance will be administered
Treatment groups
Trial outcomes
Primary outcomes
visual analogue scale (VAS)
The visual analog scale (VAS) is a validated, subjective measure for acute and chronic pain. Scores are recorded by making a handwritten mark on a 10-cm line that represents a continuum between "no pain" and "worst pain."
Secondary outcomes
Quality of Recovery - 15
The QoR-15 scale is a unidimensional measurement of quality of recovery measured in five domains: physical comfort, pain, physical independence, psychological support, and emotional state. The QoR-15 scale provides a score ranging from 0 to 150, with a high score indicating a good quality of recovery
Sponsors and contacts
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