Effect of Hormonal Cahanges During Menstrual Cycle on Subcostal Transversus Abdominis Plane Block

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age18-65
SponsorAdiyaman University Research Hospital

About this trial

Fascial plane blocks are traditionally considered regional anesthesia techniques, where a mixture of local anesthetic (LA) is injected into a plane between two fascial layers, with the aim of spreading along this anatomical plane to block the nerves lying within or passing through it . Various pathophysiological processes that alter the structure and characteristics of fasciae can affect the spread of the local anesthetic and the success of the block. Diabetes, hormonal changes, and cannabinoid use are among these factors. This study aims to investigate the effects of hormonal changes during the menstrual cycle on subcostal TAP block.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

ASA I-II, female, Laparoscopic cholecyctectomy, Subcostal TAP , 18-65 years old patient

Disqualifiers

ASA III-IV

<18 , >65 years old patients

menstrual disorders

Trial design

Design model

Parallel

Treatments tested in this trial

  • Subcostal Transversus Abdominis Plane Block

    Other intervention

    After ensuring airway safety under general anesthesia, a bilateral Transversus Abdominis Plane Block using 20 cc of 0.25% bupivacaine with a subcostal approach under ultrasound guidance will be administered

Treatment groups

80 Participants
are divided into 4 treatment groups
Group A: Group LBExperimental treatment 1 intervention
Group B: Group FBExperimental treatment 1 intervention
Group C: Group LNo intervention 0 interventions
Group D: Group FNo intervention 0 interventions

Trial outcomes

Primary outcomes

1

visual analogue scale (VAS)

The visual analog scale (VAS) is a validated, subjective measure for acute and chronic pain. Scores are recorded by making a handwritten mark on a 10-cm line that represents a continuum between "no pain" and "worst pain."

Time frame
postoperative 1st,2nd, 6.- 12.-24. hour

Secondary outcomes

1

Quality of Recovery - 15

The QoR-15 scale is a unidimensional measurement of quality of recovery measured in five domains: physical comfort, pain, physical independence, psychological support, and emotional state. The QoR-15 scale provides a score ranging from 0 to 150, with a high score indicating a good quality of recovery

Time frame
postoperative 24. hour

Other outcomes

Sponsors and contacts

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