Effect of Left Paratracheal Pressure on Cerebral Oxygenation During General Anesthesia

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-99
SponsorClinique Saint-Luc

About this trial

Left paratracheal pressure (LPP) has been proposed as an alternative to cricoid pressure to reduce the risk of regurgitation during induction of general anesthesia. Previous studies suggest that LPP can effectively compress the esophagus without significantly reducing left carotid blood flow. However, its effect on cerebral oxygenation has not yet been evaluated.

The aim of this prospective randomized crossover study is to assess whether application of LPP affects regional cerebral oxygen saturation measured by near-infrared spectroscopy (NIRS) during general anesthesia.

Seventy adult patients undergoing elective surgery under general anesthesia with tracheal intubation will be included. After induction of anesthesia and stabilization, cerebral oxygen saturation will be continuously measured under three conditions: no cervical pressure, left paratracheal pressure at 30 N, and cricoid pressure at 30 N. The order of the two pressure maneuvers will be randomized.

The primary objective is to determine the change in left regional cerebral oxygen saturation during LPP compared with baseline without cervical pressure.

Eligibility criteria

Qualifiers

Age ≥18 years

Scheduled for elective surgery requiring general anesthesia with orotracheal intubation

American Society of Anesthesiologists (ASA) physical status I to III

Ability to understand the study information

Disqualifiers

Refusal to participate

Known or suspected pregnancy

Emergency surgery

Inability to provide informed consent

Trial design

Treatments tested in this trial

  • Left Paratracheal Pressure
  • Cricoid Pressure

Treatment groups

70 Participants
are divided into 2 treatment groups

Sponsors and collaborators