Effect of Oral Astaxanthin Formula on Pulmonary Rehabilitation in Patients With COPD
ConditionCOPD
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-80
SponsorChina-Japan Friendship Hospital
About this trial
The goal of this clinical trial is to investigate whether an astaxanthin-based dietary supplement combined with a pulmonary rehabilitation training program could improve exercise capacity in patients with COPD. The main questions it aims to answer are:
• whether an astaxanthin-based dietary supplement combined with a pulmonary rehabilitation training program could improve 6MWD in patients with COPD.
The drug administration group will receive:
* Two capsules of astaxanthin formula supplement daily for 8 weeks. * Pulmonary rehabilitation training: a total of 8 weeks, 2-3 times a week.
The control group will receive a total of 8-week pulmonary rehabilitation training, 2-3 times a week.
The investigators will compare the drug administration group and the control group to see if the difference between the 2 groups reaches a minimal clinically important difference.
Eligibility criteria
Qualifiers
Patients who met the GOLD diagnostic criteria for stage II-IV COPD
Patients who met the indications for pulmonary rehabilitation training: mMRC score
3 or self-reported decline in physical function.
Disqualifiers
Hypoxemia (resting partial pressure of oxygen < 60mmHg or oxygen saturation < 88%) or patients requiring continuous oxygen therapy or with any contraindications to exercise testing (refer to the American Society of Thoracic Surgeons/American College of Chest Physicians exercise testing guidelines).
Using oral glucocorticoids
Long-term oxygen therapy
Participated in a supervised exercise program within the past 12 months
Trial design
Treatments tested in this trial
- Astaxanthin
- Pulmonary rehabilitation training
Treatment groups
140 Participants
are divided into 2 treatment groupsLocations
Sponsors and collaborators
Source ClinicalTrials.gov