Health TrialsbyHealthPanel

Effect of Parenteral Support on FibroScan in Short Bowel Syndrome

ConditionsShort Bowel SyndromeIntestinal FailureLiver Diseases
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorRigshospitalet, Denmark

About this trial

Home Parenteral Support (HPS) is a life-sustaining treatment for patients with short bowel syndrome and intestinal failure. This study aims to investigate how administration of parenteral support affects FibroScan results in order to determine optimal timing of liver assessment in this patient population.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Adult patients (≥18 years) with short bowel syndrome with capacity to give consent

Patients receiving regular PS (≥4 days/week and ≥10 liters/week)

Stable clinical condition

Disqualifiers

Known liver cirrhosis

Active infection, severe dehydration, or electrolyte disturbances

Pregnancy

Receiving IV fluids or medications on study day

Trial population

Patients with short bowel syndrome receiving regular PS

Trial design

Design model

Case-only

Time perspective

Prospective

Treatments tested in this trial

  • Fibroscan

    Diagnostic test

    Fibroscan will be perfomed while the patient receives their usual parenteral support

Treatment groups

20 Participants
are divided into 1 treatment group
Group A: Observational Cohort - patients with short bowel syndrome on parenteral support1 intervention

Trial outcomes

Primary outcomes

1

Fibroscran

Change in transient elastography (FibroScan) values before, during, and after parenteral support

Time frame
14 hours

Secondary outcomes

1

CAP score

Change in CAP score before, during, and after PS

Time frame
14 hours
2

Correlation of Fibroscan and PS

Correlation of changes in FibroScan values with PS composition and volume

Time frame
14 hours
3

Correlation of Fibroscan and other factors

Correlation with body weight, blood pressure, body fluid content, and urine output

Time frame
14 hours

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Rigshospitalet, Denmark

Lead sponsor

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: