Coronary chronic total occlusions (CTOs) are considered to increase the risk of adverse clinical outcomes. The purpose of this study was to evaluate whether long-term clinical outcomes could be improved by successful percutaneous coronary intervention (PCI) over optimal medical therapy (OMT) in CTO patients.
patients with at least one coronary CTO lesion at our hospital in between January 2011 and December 2017
(1) patients with ST-segment elevation myocardial infarction (STEMI)
(2)a history of coronary artery bypass grafting (CABG)
(3) cardiogenic shock
(4) malignant tumor. Patients were referred for PCI based on CTO-related symptoms or evidence of viability, or corresponding ischemia in the area of the CTO artery.
Patients were referred for PCI based on CTO-related symptoms or evidence of viability, or corresponding ischemia in the area of the CTO artery. The enrolled patients were divided into 2 groups, i.e., CTO-PCI group (n=187) and CTO-OMT group (n=46). The strategy to perform PCI on CTO patients was dependent on some factors, including co-morbidity, technical challenges, operators' preference
Case-control
Retrospective
PCI
Procedure/Surgerysuccessful percutaneous coronary intervention (PCI) in Coronary chronic total occlusions (CTOs) patients
OMT
Drugoptimal medical therapy (OMT) in CTO patients, such as aspirin 1td, ACEI/ARB 1td, β blocker 1td, statin 1td.
major adverse cardiac cerebrovascular events (MACCE)
including cardiac death, recurrent myocardial infarction, unplanned revascularization, and stroke.
all-cause death
all-cause death
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