About this trial
Patients who are intubated and mechanically ventilated in the intensive care unit (ICU) require repeated endotracheal suctioning to remove airway secretions. Although this procedure is necessary, it can cause a temporary collapse of lung units (alveolar derecruitment), leading to a decrease in lung volume and impaired oxygenation.
A recruitment maneuver consists of briefly applying a higher airway pressure after suctioning in order to reopen collapsed lung areas and restore lung volume. However, the clinical benefit of performing a recruitment maneuver systematically after suctioning remains uncertain.
This study aims to evaluate whether performing a recruitment maneuver immediately after closed-circuit endotracheal suctioning improves lung volume compared with suctioning alone. Lung volume will be assessed using electrical impedance tomography (EIT), a non-invasive bedside imaging technique that allows real-time monitoring of lung aeration.
In a randomized crossover design, each patient will undergo two suctioning procedures: one followed by a recruitment maneuver and one without, in a random order. The main outcome will be the change in end-expiratory lung volume 15 minutes after suctioning. The results may help optimize ventilatory care in mechanically ventilated ICU patients.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Adults aged ≥18 years
Covered by national health insurance
Admitted to the intensive care unit
Intubated and mechanically ventilated
Disqualifiers
Contraindication to electrical impedance tomography (e.g. pacemaker, implantable cardioverter-defibrillator, or implanted electrical stimulation device)
Contraindication to recruitment maneuvers (e.g. emphysema, undrained pneumothorax, hemodynamic instability)
Refractory intracranial hypertension
Acute respiratory distress syndrome requiring prone positioning
Trial design
Crossover
Treatments tested in this trial
Suction + Recruitment maneuver
Procedure/SurgeryAfter suctioning, a recruitment maneuver is applied consisting of an airway pressure of 30 cmH₂O maintained for 30 seconds, without changing the positive end-expiratory pressure.
Closed-circuit endotracheal suctioning
Procedure/SurgeryStandard closed-circuit endotracheal suctioning performed for less than 15 seconds without disconnecting the ventilator.
Treatment groups
Trial outcomes
Primary outcomes
Percentage change in end-expiratory lung volume (EELV) after suctioning
EELV assessed by end-expiratory lung impedance measured with electrical impedance tomography (PulmoVista® V500).
Secondary outcomes
Change in lung compliance
Measured from ventilator-derived respiratory mechanics.
Change in functional residual capacity (FRC)
Measured by nitrogen washout using the CARESCAPE R860 ventilator.
Change in PaO₂/FiO₂ ratio
Calculated from arterial blood gas analysis.
Sponsors and contacts
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