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Effect of Preoprative Nebulized Dexmedetomidine Compared to Nebulized Lidocaine in Attenuating Sore Throat Following Tonsillectomy In Childern.

ConditionsSore ThroatDexmedetomidine AnalgesiaTonsillectomy
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age3-15
SponsorFayoum University Hospital

About this trial

The aim of the study is to compare the effect of nebulized Dexmedetomidine compared to nebulized Lidocaine on postoperative sore throat in childern undergoing Tonsillectomy.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Age: Childern between 3:15 years old

American Society of Anesthesiologists(ASA) Physical Status I or II

Elective Tonsillectomy

Disqualifiers

Parents refusal

Presence of preoperative sore throat

Known allergy to the study drug

History of upper respiratory tract infection 2 weeks prior to surgery

Trial design

Design model

Parallel

Treatments tested in this trial

  • Group D (dexmedetomidine group)

    Drug

    group D (Dexmedetomidine group) will recieve a dose of 1 mcg/kg

  • Group L (Lidocaine group)

    Drug

    will recieve Lidocaine 2%, 1 mg/kg

Treatment groups

70 Participants
are divided into 2 treatment groups
Group A: group D (Dexmedetomidine group)Experimental treatment 1 intervention
Group B: Group L (Lidocaine group)Active comparator 1 intervention

Trial outcomes

Primary outcomes

1

Incidence of Postoperative Sore Throat (POST)

Time frame
immediately on PACU

Secondary outcomes

1

Severity of sore throat (ST)

specifically at the 4th postoperative hour. ST was scored on a four-point scale (0-3) (20) 0 =No ST 1. =mild ST (complains of ST only on asking); 2. =moderate ST (complains of ST on his/her own) 3. =severe ST (change in voice or hoarseness, associated with throat pain).

Time frame
at the 4th postoperative hour
2

*Hemodynamic Parameters

Heart Rate

Time frame
every 5 minutes intraoperatively and at 0,1,3,6,12 and 24hrs postoperatively
3

Hemodynamic Parameters

Mean Arterial Blood Pressure

Time frame
every 5 minutes intraoperatively and at 0,1,3,6,12 and 24hrs postoperatively
4

Hemodynamic Parameters

Oxygen Saturation ( SPO2 )

Time frame
every 5 minutes intraoperatively and at 0,1,3,6,12 and 24hrs postoperatively

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Fayoum University Hospital

Lead sponsor

Source ClinicalTrials.gov
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