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Effect of Prewarming Duration on Blood Flow After Colon Resection Surgery

ConditionPerioperative Hypothermia
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorÇiğdem Ünal Kantekin

About this trial

This study will examine whether warming patients before colon resection surgery improves blood flow in the fingers during early recovery from general anesthesia. It will also compare two warming durations. A total of 108 adults scheduled for elective colon resection surgery at Kayseri City Hospital will be assigned by chance to one of three groups: 10 minutes of warming before anesthesia, 30 minutes of warming before anesthesia, or no active warming before anesthesia. All three groups will receive warming during surgery as part of routine care.

Warming will be provided using a forced-air warming system. After surgery, a sensor placed on a finger will measure the perfusion index, a noninvasive indicator of blood flow, on arrival in the recovery unit and 5 and 10 minutes later. The main comparison will use the average of these three measurements. The researchers will also assess other circulation measurements, routine blood gas and lactate results, shivering, pain, the time until oral feeding begins, and wound infection during the 14 days after surgery.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Age 18 years or older.

Scheduled for elective colon resection surgery under general anesthesia.

American Society of Anesthesiologists (ASA) physical status I-III.

Willing to participate and able to provide written informed consent.

Disqualifiers

Age younger than 18 years.

Emergency surgery.

Severe vascular disease that may affect peripheral circulation, such as advanced peripheral arterial disease.

Severe cardiovascular instability.

Trial design

Design model

Parallel

Treatments tested in this trial

  • Preoperative Forced-Air Warming

    Device

    Active warming using a forced-air warming system in the preoperative preparation area before general anesthesia. The upper and lower body are warmed for 10 or 30 minutes according to randomized group assignment. Device temperature settings follow manufacturer recommendations and institutional clinical standards.

Treatment groups

108 Participants
are divided into 3 treatment groups
Group A: 10-Minute PrewarmingExperimental treatment 1 intervention
Group B: 30-Minute PrewarmingExperimental treatment 1 intervention
Group C: Control: No PrewarmingNo intervention 0 interventions

Trial outcomes

Primary outcomes

1

Mean Postoperative Perfusion Index

Perfusion index (PI) is measured noninvasively using a pulse oximeter at postanesthesia care unit (PACU) admission, 5 minutes, and 10 minutes. The primary outcome is the arithmetic mean of these three measurements. PI reflects the ratio of the pulsatile to nonpulsatile component of the photoplethysmographic signal and is used as an indicator of peripheral perfusion.

Time frame
At PACU admission and 5 and 10 minutes after admission

Secondary outcomes

1

Postoperative Pleth Variability Index

Pleth variability index (PVI) is measured noninvasively using a pulse oximeter at PACU admission, 5 minutes, and 10 minutes to compare early postoperative changes among the three study groups.

Time frame
At PACU admission and 5 and 10 minutes after admission
2

Postoperative Arterial Lactate

Arterial lactate concentration, reported in mmol/L, obtained from routine arterial blood gas analysis at postanesthesia care unit (PACU) admission. No additional arterial sampling is performed solely for this study.

Time frame
At postanesthesia care unit (PACU) admission (0 minutes)
3

Postoperative Arterial pH

Arterial pH obtained from routine arterial blood gas analysis at postanesthesia care unit (PACU) admission.

Time frame
At postanesthesia care unit (PACU) admission (0 minutes)
4

Postoperative Arterial Carbon Dioxide Partial Pressure

Arterial carbon dioxide partial pressure (PaCO2), reported in mmHg, obtained from routine arterial blood gas analysis at postanesthesia care unit (PACU) admission.

Time frame
At postanesthesia care unit (PACU) admission (0 minutes)

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Çiğdem Ünal Kantekin

Lead sponsor

Kayseri City Hospital

Sponsor institution

Source ClinicalTrials.gov

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