Effect of Regional Anesthesia or Intravenous Infusion of Lidocaine on Morphine Use After Scoliosis Repair Surgery

ConditionScoliosis
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age12-25
SponsorAssaf-Harofeh Medical Center

About this trial

The goal of the surgical correction of scoliosis is to prevent progression of the curve or progression of restrictive lung disease. After scoliosis surgery, patients experience severe pain. The standard treatment for pain relief after scoliosis surgery is the administration of opiates. However, treatment with these substances involves side effects such as respiratory depression, nausea and vomiting, inhibition of bowel activity and itching. To lower the dose of opiates, different types of painkillers and other techniques can be added.

The purpose of the study is to compare the effect of instillation of lidocaine (which is an analgesic and anti-inflammatory) or regional anesthesia using Erector spinae plane on the dose of morphine consumption, the intensity of pain, the side effects and the quality of recovery during the first 48 hours after surgery to repair scoliosis.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

None

Disqualifiers

None

Trial design

Design model

Parallel

Treatments tested in this trial

  • Lidocaine

    Drug

    a local anesthetic drug of the amino amide type

Treatment groups

105 Participants
are divided into 3 treatment groups
Group A: ControlNo intervention 0 interventions
Group B: Erector spinae plane blockActive comparator 1 intervention
Group C: LidocaineActive comparator 1 intervention

Trial outcomes

Primary outcomes

1

Morphine consumption

Dosage of morphine consumption in milligrams that the patients will consume in by pressing on the PCA device in the first 48 hours after surgery to correct scoliosis

Time frame
48 hours after surgery

Secondary outcomes

1

Quality of recovery

The patient will fill the QOR15 questionnaire for Quality of recovery

Time frame
72 hours after surgery
2

Pain intensity,

Monitoring the effect of treatments on pain intensity during the first 48 hours after surgery. Using patients' reported NRS scale 0-10 with 0 meaning no pain at all and 10 meaning the worst imaginable pain.

Time frame
48 hours after surgery. The pain will be monitored at 1, 6, 12, 24 and 48 hours after the surgery.

Other outcomes

Sponsors and contacts

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