Effect of Sage Extract Supplementation on Cognitive Function in Middle-Aged Men and Women

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age40-60
SponsorESM Technologies, LLC

About this trial

Sage (Salvia officinalis) has been reported to have antioxidant, anti-inflammatory, and neuroprotective properties. Several studies indicate that sage supplementation can improve cognitive function. However, more research is needed. The purpose of this study is to examine how sage supplementation affects cognitive function and reaction times in middle-aged men and women.

Eligibility criteria

Qualifiers

BMI 18.5-34.9 (inclusive) with a goal of being < 30 on average

Subject agrees to maintain their existing dietary patterns throughout the study period.

Subject agrees to refrain from alcohol, caffeine, and strenuous exercise for 24 hours before each test day.

Subject is willing and able to comply with the study protocol.

Disqualifiers

Individuals with a personal history of a psychiatric disorder.

Individuals who are determined to have liver, renal, cardiovascular, or other metabolic disease.

Current or recent (< 4 weeks) use of any dietary supplements (e.g., choline, lecithin, ginseng, ginkgo biloba, ashwagandha, Bacopa Monnieri, Paullina cupana, Rhodiola rosea, L-theanine, omega-3 fats, Prevagen, etc.), or currently prescribed medications (e.g., Adderall, Mydayis, Ritalin, Concerta, Mythylin, Provigil, Namenda), that may affect cognitive function (focus, concentration, memory, reaction time, energy, etc.).

Alcohol consumption (>2 standard alcoholic drinks/day or >10 drinks/week) or drug abuse/dependence (including regular marijuana or THC use).

Trial design

Treatments tested in this trial

  • SageXtra
  • Placebo

Treatment groups

64 Participants
are divided into 2 treatment groups

Sponsors and collaborators

ESM Technologies, LLC

Lead sponsor

Exercise & Sport Nutrition Lab, Texas A&M University

Collaborator