Effect of Soya Bean on the Female Reproductive Hormones and Menopausal Symptoms

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
AgeNot listed
SponsorAlex Ekwueme Federal University Teaching Hospital

About this trial

Menopause is one of the most emotionally, physically and Psychological miserable times in a woman's life.It occurs following cessation of menses resulting in the decline of endogenous estrogen. Phytoestrogens are natural plant derived compounds found in a wide variety of foods and soy bean is considered to be the richest source of plant estrogens. Current advances in management of menopause have relied on the use of hormone replacement therapy; however they are associated with adverse side effects if used over a long period of time. Currently, there is varying opinion regarding the physiological impact of soy bean consumption and results of studies are sparse and inconclusive. Hence, the need to determine the effect of soya bean consumption on the female reproductive hormones and relief of menopausal symptoms

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Women who gave consent

Absence of Menses for more than 1year that is not due to medical treatment

More than 40years of age

Disqualifiers

Women on hormone replacement therapy

Women on any hormonal medication

Allergy to soya products.

40year old or lesser

Trial design

Design model

Parallel

Treatments tested in this trial

  • Soy Bean

    Dietary supplement

    Soya bean is a phytoestrogen

Treatment groups

69 Participants
are divided into 3 treatment groups
Group A: 50g Soya bean GroupExperimental treatment 1 intervention
Group B: 100g Soya bean groupExperimental treatment 1 intervention
Group C: Normal Diet groupNo intervention 0 interventions

Trial outcomes

Primary outcomes

1

Changes in the Reproductive hormones

Analysis of the Serum estrogen, progesterone, follicle stimulating hormone, lutenizing hormone and antimullerian hormone

Time frame
28days

Secondary outcomes

1

Changes in menopausal symtoms

Using questionaire and standardised tools to collect information about menopausal symtoms

Time frame
28days

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

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