About this trial
The aim of this trial is to test the efficacy of regular resistance exercise in early pregnancy to prevent gestational diabetes mellitus in overweight/ obese pregnant women.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
BMI≥25 kg/m2
Singleton pregnancies
Disqualifiers
Chronic hypertension
Pre-pregnancy DM (type I or 2 diabetes mellitus)
Cardiovascular disease
History of preterm delivery
Trial design
Parallel
Treatments tested in this trial
Resistance exercise
Other interventionThe intervention group will train 3 times per week (30 minutes with 15 min warm-up). The resistance exercise is described as the voluntary contraction of the skeletal muscle of a particular muscle group against some type of resistance, using light weights, elastic bands or the weight of the body itself. Patients will be offered online sessions, they will receive a document with recommendations and a link to the videos with instructions. .
Treatment groups
Trial outcomes
Primary outcomes
Gestational diabetes
Gestational diabetes mellitus (GDM) is defined as any degree of glucose intolerance with onset or first recognition during pregnancy: * O'Sullivan Test: if this is pathological; * SOG with 100 gr of glucose (GDM is diagnosed when 2 or more altered values: basal glycemia \>105 mg / dl, at 1 hour \>190 mg / dl, at 2h glycemia \>165 mg / dl, at 3h glycemia \>145 gr/dl).
Secondary outcomes
Weight gain and excessive body weight gain
Determined by IOM (Institute of Medicine) guideline
Maternal and fetal pregnancy outcomes
Newborn weight, preterm deliveries, Apgar score and pH of umbilical cord, duration of labour and delivery mode
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