Health TrialsbyHealthPanel

Effect of Vitamin D and Branched-chain Amino Acids on Physical Performance and Biomarkers of Muscle Fatigue in Runners

ConditionsHealthy Adult MaleRunners
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexMale
Age25-44
SponsorPedro Julian Flores Moreno

About this trial

Muscle fatigue caused by physical training is understood as a condition related to the inability to maintain action potential, derived from the alteration in skeletal muscle homeostasis. In long-distance recreational runners, prolonged physical work is performed while maintaining the level of intensity, where a level of fatigue intervenes, which overlaps and generates tiredness to execute the movement continuously. In the last 10 years, sports supplementation has been explored as an aid to increase physical performance, improve muscle recovery and prevent sports injuries.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Adults aged 25 to 44

Men

Agree to participate in the study

Sign a consent form

Disqualifiers

Have a previous diagnosis of liver disease, asthma, hypertension, diabetes, cancer, anemia

Have a previous diagnosis of a neurological disorder (Alzheimer's disease, Parkinson's disease, epilepsy)

Have a musculoskeletal disability

Be on medication or supplementation

Trial design

Design model

Parallel

Treatments tested in this trial

  • Training program

    Other intervention

    Aerobic training program (60-90% of maximum aerobic speed)

  • Branched-Chain Amino Acids

    Dietary supplement

    Branched-chain amino acids (5 gr/day)

  • Vitamin D

    Dietary supplement

    Vitamin D (1000 IU/day)

  • Placebo 1

    Other intervention

    Placebo 1 (5gr/day)

  • Placebo 2

    Other intervention

    Placebo 2 (1 tablet/day)

Treatment groups

64 Participants
are divided into 4 treatment groups
Group A: Group 1 (TP + BCAA + VitD)Experimental treatment 3 interventions
Group B: Group 2 (TP + BCAA + P2)Experimental treatment 3 interventions
Group C: Group 3 (TP + VitD + P1)Experimental treatment 3 interventions
Group D: Group 4 (TP + P1+ P2)Placebo comparator 3 interventions

Trial outcomes

Primary outcomes

1

Changes in lactate levels compared to the placebo group

mMol/L

Time frame
8 weeks
2

Changes in interleukin-6 levels compared to the placebo group

pg/ml

Time frame
8 weeks
3

Changes in cratine kinase levels compared to the placebo group

U/L

Time frame
8 weeks
4

Changes in testosterone cortisol ratio compared to the placebo group

mcg/dL

Time frame
8 weeks

Secondary outcomes

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Pedro Julian Flores Moreno

Lead sponsor

Universidad de Colima

Sponsor institution

Claudia Ivette Gamboa Gomez

Collaborator

Fabian Rojas Larios

Collaborator

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: