Effectiveness and Safety of Sequential Triple Combination Therapy (Amlodipine/Losartan/Chlorthalidone) in Korean Patients With Hypertension

ConditionHypertension
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
AgeNot listed
SponsorHanmi Pharmaceutical Company Limited

About this trial

A multicenter, prospective, non-interventional, observational study to evaluate effectiveness and safety of sequential triple combination therapy (amlodipine/losartan/chlorthalidone) in Korean patients with hypertension

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Korean patients aged 19 years or older diagnosed with hypertension

Individuals newly diagnosed with hypertension or currently taking a single antihypertensive drug

Individuals for whom administration of Amoprel tablets has been determined based on the researcher's medical judgment

Individuals who have heard an explanation of this study and have voluntarily given written consent to participate in the study

Disqualifiers

Individuals falling under the contraindications listed in the precautions for use of Amoprel Tab. or Amozartan Plus Tab.

Pregnant women, women who may be pregnant, and nursing mothers

Individuals currently participating in an interventional study

Individuals deemed unsuitable for participation in this study by the researcher for other reasons

Trial population

General hospital

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

  • AMOPREL TAB 1.67/16.67/4.17mg

    Drug

    Follow-up of subjects prescribed medication in a non-intervention study

Treatment groups

No treatment groups listed

Trial outcomes

Primary outcomes

1

The change in Systolic Blood Pressure (SBP) relative to baseline

Time frame
the 6-month time

Secondary outcomes

1

effectiveness of sequential triple combination therapy (amlodipine/losartan/chlorthalidone)

Change from baseline in Systolic Blood Pressure (SBP) and Diastolic Blood Pressure (DBP) at 2 and 4 months, and change from baseline in DBP at 6 months

Time frame
2, 4, 6 months
2

Prescription patterns of a triple-therapy-based stepwise treatment strategy

Proportion of Participants by Study Drug Dosage at Months 2, 4, and 6

Time frame
2, 4, 6 months
3

safety of sequential triple combination therapy (amlodipine/losartan/chlorthalidone)

Incidence of Adverse Events During the 6-Month Follow-up Period

Time frame
2, 4 , 6 months

Other outcomes

Sponsors and contacts

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