The overall objective is to evaluate the effectiveness of a school-centered primary and secondary prevention program on the prevalence of latent rheumatic heart disease among schoolchildren in Nepal, and to investigate the role of socioeconomic and environmental factors in the development and progression of rheumatic heart disease.
Age 5-16 years
Attending Tulsi Secondary Boarding School in Tulsipur, Nepal.
Children / primary caregivers not providing informed consent to participate
Children not attending Tulsi Secondary Boarding School in Tulsipur.
Single group
School nurse program
Other interventionSchool nurse program providing health care through assessment, intervention and follow-up of group A β-hemolytic streptococcal pharyngitis and facilitation of secondary antibiotic prophylaxis for children with latent rheumatic heart disease.
Prevalence of definite or borderline Rheumatic Heart Disease
Prevalence of definite or borderline Rheumatic Heart Disease according to the criteria of the World Heart Federation as assessed by systematic echocardiographic screening
Group A β-hemolytic streptococcal pharyngitis
Number of patients with group A β-hemolytic streptococcal pharyngitis within study participation
Acute rheumatic fever
Number of patients with acute rheumatic fever within study participation
Rheumatic heart disease
Number of patients with rheumatic heart disease within study participation
Adverse reactions to penicillin injections
Number of patients with adverse reactions to penicillin injections within study participation
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