Effectiveness of Micro Connective Tissue Graft for Treatment of Multiple Adjacent Gingival Recession Defects

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-60
SponsorGöteborg University

About this trial

The objective of this project is to evaluate 1-year outcomes of treatment of MAGRD using a modified coronally advanced tunnel technique (MCAT) with either conventional CTG (control group) or micro-CTG (test group).

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

age ≥18 years,

systemically healthy,

presenting with a minimum of 4 and a maximum of 6 adjacent RT1/RT2 recessions, located in the maxilla or mandible with an apico-coronal extension (i.e. recession depth) of ≥2 mm,

Full-Mouth Plaque Score (FMPS) <20%,

Disqualifiers

pregnancy or lactation,

tobacco smoking,

uncontrolled medical condition,

medication that can affect gingival conditions.

Trial design

Design model

Parallel

Treatments tested in this trial

  • Coronally Advanced Flap combined with a Connective Tissue Graft

    Procedure/Surgery

    Multiple adjacent gingival recession defects will be covered by coronally advanced flap combined with a connective tissue graft harvested from the palate.

  • Coronally Advanced Flap combined with micro Connective Tissue Graft

    Procedure/Surgery

    Multiple adjacent gingival recession defects will be covered by coronally advanced flap combined with multiple micro connective tissue graft harvested from the palate.

  • Division of the Connective Tissue Graft into multiple micro Connective Tissue Grafts

    Device

    The harvested connective tissue graft is divided in multiple micro connective tissue grafts with a scalpel blade before being placed on the recipient site.

Treatment groups

30 Participants
are divided into 2 treatment groups
Group A: Connective Tissue GraftActive comparator 1 intervention
Group B: Micro Connective Tissue GraftExperimental treatment 2 interventions

Trial outcomes

Primary outcomes

1

Mean mid-facial recession coverage (mRC)

Percentage of the exposed tooth root covered after surgical intervention

Time frame
up to 1 year

Secondary outcomes

1

Complete Root Coverage (CRC)

Frequency of complete root coverage

Time frame
up to 1 year
2

Changes of Keratinized Tissue Width (KTW)

Measured as the distance from the muco-gingival-junction to the gingival margin

Time frame
up to 1 year
3

Changes of Gingival Thickness (GT)

Measured 3 mm apically from the free gingival margin at the mid-buccal aspect of the tooth

Time frame
up to 1 year
4

Patient Morbidity

Measured with Visual Analogue Scale (VAS), which consists of a 10cm line, with two end points representing 0 ('no pain') and 10 ('pain as bad as it could possibly be')

Time frame
up to 2 weeks

Other outcomes

Sponsors and contacts

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