The goal of this clinical trial is to evaluate whether respiratory nursing interventions can improve respiratory outcomes in patients hospitalized with acute exacerbation of Chronic Obstructive Pulmonary Disease (COPD). The main questions it aims to answer are:
Do respiratory nursing interventions improve dyspnea levels measured by the Modified Medical Research Council (mMRC) Dyspnea Scale? Do these interventions improve oxygen saturation and pulmonary function (FVC, FEV1, and FEV1/FVC ratio)?
Researchers will compare patients receiving respiratory nursing interventions plus routine hospital care with patients receiving routine hospital care alone to determine whether the interventions improve respiratory outcomes.
Participants will:
Undergo baseline assessment using the mMRC Dyspnea Scale, pulse oximetry, and pulmonary function tests.
Receive either respiratory nursing interventions (deep breathing exercises, chest percussion, postural drainage, and lukewarm water intake) along with routine care or routine hospital care alone.
Be reassessed after the intervention period using the same respiratory outcome measures.
Diagnosed cases of COPD admitted for acute exacerbation according to Global Initiative for Chronic Obstructive Lung Disease.
Adults aged > 40 years (WHO, 2023; GOLD, 2024).
Both genders (male & female).
Hemodynamically stable at the time of enrollment in terms of vital signs (e.g., blood pressure > 90/60 mmHg, heart rate between 60-100 bpm) to safely undergo nursing interventions without acute risk (Jarhyan et al., 2021).
Dyspnea due to cardio-pulmonary disease or other co-morbidities.
Patients on mechanical ventilation and ICU admission.
Patients with mental disorders.
Patients with upper airway obstruction.
Parallel
Experimental group will receive nursing interventions such as deep breathing exercise, chest percussions along with standard care.
Other interventionThe intervention consists of a structured package of respiratory nursing interventions provided in addition to routine hospital care for patients hospitalized with acute exacerbation of Chronic Obstructive Pulmonary Disease (COPD). It includes deep breathing exercises, chest percussion, postural drainage, and lukewarm water intake, administered by trained nursing staff according to a standardized protocol during hospitalization. These combined interventions aim to enhance airway clearance, improve ventilation, and reduce mucus viscosity, thereby improving dyspnea, oxygen saturation, and pulmonary function outcomes. The integration of multiple respiratory nursing techniques as an add-on to routine care distinguishes this intervention from standard management practices.
Change in Dyspnea Severity
Change in dyspnea severity measured using the Modified Medical Research Council Dyspnea Scale to assess the dyspnea affecting functioning in patients with acute exacerbation of Chronic Obstructive Pulmonary Disease. 0-5 Scale (0 Minimal functioning impairment and 4 maximum functioning impairment)
Change in Pulmonary Function
Change in pulmonary function parameters including Forced Vital Capacity (FVC), Forced Expiratory Volume in one second (FEV1), and FEV1/FVC ratio measured using pulmonary function tests to determine the impact of respiratory nursing interventions in COPD patients with acute exacerbation. Normal is greater than 70%. Less than 70% means decreased pulmonary function.
Change in Oxygen Saturation (SpO₂)
Change in oxygen saturation levels measured by pulse oximetry to evaluate the impact of respiratory nursing interventions on oxygenation status in patients hospitalized with acute exacerbation of Chronic Obstructive Pulmonary Disease. Low Saturation Less than 88% and Normal greater than 95%.
Click on the lead sponsor to view all of their trials.
This trial is not recruiting at the moment. You can still explore other options:
