Effectiveness of the Personalized Responses & Integrated Systems for Metabolism (PRISM) on Improving Insulin Resistance Among Adults With Metabolic Syndrome: A Pilot Study (PRISM-I)

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age21-70
SponsorNational University Health System, Singapore

About this trial

The primary objective of the Personalized Responses \& Integrated Systems for Metabolism (PRISM-I) pilot study is to assess the feasibility of conducting a definitive randomized controlled trial evaluating precision lifestyle interventions for improving insulin resistance in adults with metabolic syndrome.

Eligibility criteria

Qualifiers

(1) adults aged 21-70 years old;

(2) willing and able to comply with using a CGM, smart ring, food logging app

(3) able to provide written informed consent;

(4) English-speaking and literate;

Disqualifiers

(1) on insulin therapy;

(2) are pregnant or lactating;

(3) have a medical condition or are on a treatment that may interfere with study participation or metabolic assessments, as determined by the study investigators;

(4) currently participating in other lifestyle modification programs.

Trial design

Treatments tested in this trial

  • Time-restricted eating
  • Physical Activity
  • Low Glycemic Load diet
  • Sleep hygiene

Treatment groups

200 Participants
are divided into 2 treatment groups