About this trial
The primary objective of the Personalized Responses \& Integrated Systems for Metabolism (PRISM-I) pilot study is to assess the feasibility of conducting a definitive randomized controlled trial evaluating precision lifestyle interventions for improving insulin resistance in adults with metabolic syndrome.
Eligibility criteria
Qualifiers
(1) adults aged 21-70 years old;
(2) willing and able to comply with using a CGM, smart ring, food logging app
(3) able to provide written informed consent;
(4) English-speaking and literate;
Disqualifiers
(1) on insulin therapy;
(2) are pregnant or lactating;
(3) have a medical condition or are on a treatment that may interfere with study participation or metabolic assessments, as determined by the study investigators;
(4) currently participating in other lifestyle modification programs.
Trial design
Treatments tested in this trial
- Time-restricted eating
- Physical Activity
- Low Glycemic Load diet
- Sleep hygiene