About this trial
Inhalational anesthetics (IAs) are widely used in surgery and experimental research. IAs, in addition to their medical significance, are a major source of chemical contamination in the operating rooms (ORs).Exposure to IAs in ORs personnel results in reproductive effects, including infertility , spontaneous abortions , congenital diseases , psychological and neurological disturbances, hepatotoxicity , and genotoxicity .The metabolites of sevoflurane include hexafluoroisopropanol (HFIP) and inorganic fluoride (IF). The hospital's engineering department installed an air extractor with the objective to reduce the anesthetic gas concentrations during pediatric anesthesia induction. The investigators are interested in checking if the new technique also has an influence in decreasing the level of Sevoflurane breathed in by the anesthesiologist.The investigators purpose is to detect the presence of desfluoroisopropanolol in the urine of ten anesthesiologists who used sevoflurane to induce children with a mask during an eight-hour session in the induction room (IR) One session will be conducted without the use of the air extractor and the other with the air extractor. After 24 hours, a urine sample will be taken and sent to the Toxicology Unit.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
None
Disqualifiers
None
Trial population
Ten anesthesiologists that work in Pediatric Induction Room using anesthesia induction with sevoflurane delivery with mask
Trial design
Cohort
Prospective
Treatments tested in this trial
Urine analysis to determine the presence of hexafluoroisopropanol
Diagnostic testanalysis of sevoflurane metabolites in urine
Treatment groups
Trial outcomes
Primary outcomes
Presence of sevoflurane metabolite, hexafluoroisopropanol in urine
hexafluoroisopropanol is the metabolism of the sevofluorane
Locations
Sponsors and contacts
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