Effects of a Brown Seaweed Tart Cherry Blend in Mild-moderate Hypertension

ConditionHypertension
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-65
SponsorUniversity of Central Lancashire

About this trial

The brown seaweed species Ascophyllum nodosum is rich in bioactive polysaccharides, proteins, peptides, lipids, pigments, and polyphenols. Similarly, Montmorency tart cherry (Prunus cerasus L.) is high in anthocyanins and polyphenols. Both substances have antioxidant, anti-inflammatory, and vasodilatory properties that target mechanisms central to hypertension and cardiometabolic diseases.

Dietary interventions to improve cardiovascular health are highly sought after as they possess less risk and financial burden than pharmacological drugs. Previous randomized trial has shown that both brown seaweed and tart cherry supplementation can improving systolic blood pressure and other cardiovascular/ blood lipids. However, to date, no research has explored a seaweed - tart cherry blend using a placebo randomized intervention in patients with hypertension.

The primary purpose of the proposed investigation is to test the ability of a seaweed - tart cherry supplementation blend to improve cardiometabolic parameters in participants with mild-moderate hypertension using a pilot/ feasibility study.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Aged from 18-65 years

Systolic blood pressure 120 to 139 mmHg

Not taking prescribed medicine for blood pressure management

Ability to complete written questionnaires independently

Disqualifiers

Diagnosed with diabetes mellitus and/ or coronary heart disease

Pregnant and lactating women

Allergy to peppermint

Habitual consumption of peppermint products

Trial design

Design model

Parallel

Treatments tested in this trial

  • Brown seaweed and tart cherry blend

    Dietary supplement

    Blend of brown seaweed and tart cherry blend taken twice daily

  • Placebo

    Other intervention

    Identical in taste and colour to the supplement, but with no brown seaweed or tart cherry.

Treatment groups

30 Participants
are divided into 2 treatment groups
Group A: PlaceboPlacebo comparator 1 intervention
Group B: Brown seaweed and tart cherry blendExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Systolic blood pressure

Systolic blood pressure - measured using a digital blood pressure monitor

Time frame
Baseline
2

Systolic blood pressure

Systolic blood pressure - measured using a digital blood pressure monitor

Time frame
20 days

Secondary outcomes

1

Diastolic blood pressure

Diastolic blood pressure - measured using a digital blood pressure monitor

Time frame
Baseline
2

Diastolic blood pressure

Diastolic blood pressure - measured using a digital blood pressure monitor

Time frame
20 days
3

Percent bodyfat and fat mass

Participants percentage composition of fat - measured using bio-electrical impedance

Time frame
Baseline
4

Percent bodyfat and fat mass

Participants percentage composition of fat - measured using bio-electrical impedance

Time frame
20 days

Other outcomes

Sponsors and contacts

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