Effects of Aerobic Exercise on Skeletal Muscle Remodeling in Colorectal Cancer
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorAdventHealth Translational Research Institute
About this trial
The goal of this clinical trial is to quantify the effects of aerobic exercise training compared to attention control on intermuscular adipose tissue in colorectal cancer survivors.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Age ≥18 years
Histologically confirmed stage I, II, or III colon or rectal cancer
Completed surgical resection with curative intent
Completed other cancer-directed treatments
Disqualifiers
Evidence of metastatic or recurrent colorectal cancer
Concurrently actively treated other (non-colorectal) cancer
Scheduled to receive other postoperative cancer-directed treatment(s)
Currently pregnant, breastfeeding, or planning to become pregnant within the next 24 weeks
Trial design
Design model
Parallel
Treatments tested in this trial
Aerobic exercise
BehavioralModerate- to vigorous-intensity aerobic exercise
Progressive stretching
BehavioralStatistic stretching of eight major muscle groups
Treatment groups
70 Participants
are divided into 2 treatment groupsGroup A: Attention controlSham comparator 1 intervention
Group B: Aerobic exerciseExperimental treatment 1 intervention
Trial outcomes
Primary outcomes
1
Whole-Body Intermuscular Adipose Tissue
Mean (kg) whole-body intermuscular adipose tissue quantified using magnetic resonance imaging.
Time frame
up to Week 12Sponsors and contacts
Click on the lead sponsor to view all of their trials.
AdventHealth Translational Research Institute
Lead sponsor
National Cancer Institute (NCI)
Collaborator
Source ClinicalTrials.gov