Effects of Circadian Rhythm on Glycemic Regulation During Continuous Moderate Exercise and Intense Intermittent Disease in Adolescents Living With Type 1 Diabetes

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age10-16
SponsorLille University

About this trial

Interventional research with minimal risks and constraints on the effects of circadian rhythm on glycemic regulation during intense moderate, continuous and intermittent exercise in adolescents living with type 1 diabetes

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Children and adolescents aged 10 to 16;

Living with type 1 diabetes for at least 1 year with HbA1c less than or equal to 12%;

Socially insured ;

Having given their written consent to participate in the research, as well as that of their legal guardians;

Disqualifiers

Clinically significant microvascular complications: nephropathy (estimated glomerular filtration rate less than 40 ml/min), neuropathy or severe proliferative retinopathy as assessed by the investigator;

Recent acute macrovascular event (< 3 months), e.g. acute coronary syndrome or cardiac surgery;

Abnormal blood picture and/or anemia;

Current pregnancy;

Trial design

Design model

Crossover

Treatments tested in this trial

  • physical test

    Other intervention

    continuous and intermittent exercise on cycloergometer

Treatment groups

18 Participants
are divided into 4 treatment groups
Group A: Continuous - morningExperimental treatment 0 interventions
Group B: Continuous - afternoonExperimental treatment 1 intervention
Group C: Intermittent - morningExperimental treatment 0 interventions
Group D: Intermittent - afternoonExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Comparison of glycemic variation between the 4 conditions

Observation of time in target, time in hypoglycemia and time in hyperglycemia

Time frame
1 year 10 months september 2026

Secondary outcomes

Other outcomes

Sponsors and contacts

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