Health TrialsbyHealthPanel

Effects of Different Acupuncture Techniques on the Success Rate in Patients With Recurrent Implantation Failure

ConditionImplantation Failure
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
AgeUp to 39
SponsorCui Hong Zheng

About this trial

To conduct a multi-center, randomized, controlled clinical study aimed at formally evaluating the impact of different acupuncture methods on the success rate in patients with recurrent implantation failure

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Meets the criteria for RIF diagnosis (≥ 3 instances of unsuccessful transfer of high-quality embryos).

Age: < 40 years.

Planning for a cycle involving the transfer of frozen-thawed embryos (FET).

Possession of a transplantable frozen blastocyst (≥3BB).

Disqualifiers

Individuals planning to undergo preimplantation genetic diagnosis (PGD).

Recipients of egg donations.

Chromosomal abnormalities in either spouse or one partner (excluding chromosomal polymorphisms).

Patients with known embryo-related factors leading to implantation failure.

Trial design

Design model

Parallel

Treatments tested in this trial

  • Placebo Group

    Device

    nonpenetrating placebo needles

  • acupuncture group 1

    Device

    indwelling intradermal needles

  • acupuncture group 2

    Device

    combining fire needle and regular acupuncture

Treatment groups

312 Participants
are divided into 3 treatment groups
Group A: placebo acupuncture groupPlacebo comparator 1 intervention
Group B: acupuncture group 1Experimental treatment 1 intervention
Group C: acupuncture group 2Experimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

clinical pregnancy

defined as ultrasonographic detection of an intrauterine gestational sac following embryo transfer

Time frame
2 years

Secondary outcomes

1

β-hCG-positive pregnancy

defined as serum β-hCG concentration \>10 mIU/mL on day 14 post-transfer

Time frame
2 years
2

live birth

defined as the delivery of 1 or more living infants at greater than 20 weeks' gestation or birth weight of at least 400 g

Time frame
3 years

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Cui Hong Zheng

Lead sponsor

Huazhong University of Science and Technology

Sponsor institution

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: