Effects of EMDR on Psychological Symptoms and EEG Findings in Trauma-Exposed Individuals

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-50
SponsorIstanbul Galata University

About this trial

This study will examine the effects of Eye Movement Desensitization and Reprocessing (EMDR) group therapy on adults who experienced the April 2025 Silivri earthquake in Turkey. Participants will be randomly assigned to either an EMDR intervention group or a waitlist control group. Psychological symptoms will be measured using the PTSD Checklist for DSM-5 (PCL-5), the Depression, Anxiety, and Stress Scale (DASS-21), the Short Form Health Survey (SF-36), and the Pittsburgh Sleep Quality Index (PSQI). Quantitative EEG (QEEG) recordings will also be collected before and after the intervention to assess changes in brain activity related to emotional regulation and trauma processing. The goal of the study is to evaluate whether EMDR produces both clinical and neurophysiological improvements in trauma-exposed individuals.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Meeting DSM-5 criteria for posttraumatic stress symptoms following the April 2025 Silivri earthquake

Age between 18 and 50 years

Either medication-free for at least 1 month or on a stable dose of psychotropic medication

No medical contraindications for EEG recording (e.g., no epilepsy, no metal implants)

Disqualifiers

Current diagnosis of schizophrenia, bipolar disorder, or a neurological disorder

Receiving psychotherapy

Inability to attend sessions regularly due to logistical or cognitive limitations

Trial design

Design model

Parallel

Treatments tested in this trial

  • Eye Movement Desensitization and Reprocessing (EMDR) Group Therapy

    Behavioral

    Sessions conducted in groups with one therapist and one co-therapist; each session follows the EMDR standard protocol.

Treatment groups

40 Participants
are divided into 2 treatment groups
Group A: EMDR GroupExperimental treatment 1 intervention
Group B: Waitlist ControlNo intervention 0 interventions

Trial outcomes

Primary outcomes

1

Change in Posttraumatic Stress Symptoms (PCL-5)

The PTSD Checklist for DSM-5 (PCL-5) is a 20-item self-report scale measuring the severity of posttraumatic stress disorder symptoms according to DSM-5 criteria. Scores range from 0 to 80, with higher scores indicating more severe PTSD symptoms. Change in total score from baseline (pre-intervention) to post-intervention will be assessed.

Time frame
Baseline (Pre-intervention, T1; Week 0) and Post-intervention (T2; Week 6, after completion of EMDR intervention)
2

Change in Quantitative EEG (QEEG) Power Spectral Measures

EEG recordings will be collected using the Neuron-Spectrum-5 device according to the international 10-20 system. Power spectral analyses will be performed across frequency bands (delta, theta, alpha, beta, high beta). Changes in absolute and relative power from baseline to post-intervention will be examined.

Time frame
Baseline (Pre-intervention, T1; Week 0) and Post-intervention (T2; Week 6, after completion of EMDR intervention)

Secondary outcomes

1

Change in Quality of Life (SF-36)

The Short Form Health Survey (SF-36) is a 36-item measure of health-related quality of life, covering physical functioning, role limitations, pain, general health, vitality, social functioning, and emotional well-being. Scores range from 0 to 100, with higher scores reflecting better quality of life. Change in domain scores will be assessed from baseline to post-intervention.

Time frame
Baseline (Pre-intervention, T1; Week 0) and Post-intervention (T2; Week 6, after completion of EMDR intervention)
2

Change in Depression, Anxiety, and Stress (DASS-21)

The Depression, Anxiety, and Stress Scale-21 (DASS-21) is a 21-item self-report instrument measuring emotional distress across three subscales (depression, anxiety, stress). Scores range from 0 to 42 for each subscale, with higher scores indicating greater severity. Change in scores will be assessed from baseline to post-intervention.

Time frame
Baseline (Pre-intervention, T1; Week 0) and Post-intervention (T2; Week 6, after completion of EMDR intervention)
3

Change in Sleep Quality (PSQI)

The Pittsburgh Sleep Quality Index (PSQI) is a 19-item self-report questionnaire assessing sleep quality and disturbances over the past month. Scores range from 0 to 21, with higher scores indicating poorer sleep quality. Change in total score will be assessed from baseline to post-intervention.

Time frame
Baseline (Pre-intervention, T1; Week 0) and Post-intervention (T2; Week 6, after completion of EMDR intervention)

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

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