Effects of Exercise in Patients With Repaired Coarctation of the Aorta
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorUniversity Medical Centre Ljubljana
About this trial
This interventional study will investigate the effects of high-intensity interval training (HIIT) in adults with repaired coarctation of the aorta. Participants will be randomised into three groups: HIIT performed at home, HIIT performed in a supervised outpatient setting, or a control group receiving usual care. The two HIIT protocols will be identical in intensity and progression, individually prescribed for each patient.
The study will evaluate the effects of HIIT on exercise capacity, health-related quality of life, blood pressure response to exercise, and other select measures of cardiovascular health, including vascular stiffness and endothelial function. In addition, the study will examine the acute effects of a single exercise session on arterial stiffness.
Eligibility criteria
Qualifiers
surgically repaired coarctation of the aorta,
age at least 18 years, and
signed informed consent form.
Disqualifiers
residual aortic stenosis (gradient across the narrowing >20 mmHg),
presence of ascending aortic aneurysm,
recent major cardiovascular event or other event requiring hospitalization (event less than 2 months before inclusion),
unstable rhythm disturbances,
Trial design
Treatments tested in this trial
- Outpatient high-intensity interval training (HIIT)
- Home-based high-intensity interval training (HIIT)
Treatment groups
45 Participants
are divided into 3 treatment groupsSponsors and collaborators
University Medical Centre Ljubljana
Lead sponsor
University Medical Centre Maribor
Collaborator
Source ClinicalTrials.gov