About this trial
This study will use a randomized, double-blind clinical trial to evaluate the effects of eight-week HIIT and MICT exercise programs on cardiorespiratory fitness, the testosterone/cortisol ratio, and mental health in 68 healthy, moderately active young adults aged 18 to 21. Participants will be assigned to parallel groups based on their sex and training type (HIIT men, HIIT women, MICT men, MICT women). The key metrics will be measured both before and after the intervention period to assess the impact of the different training regimens.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Men and women aged 18 to 21.
Lead a sedentary or moderately active lifestyle (IPAQ ≤600 METs-min/week).
Subjects diagnosed by a physician as fit for physical exercise.
Informed consent form signed by the study subjects.
Disqualifiers
Subjects with any motor disability.
Pregnant women.
Subjects with metabolic disorders.
Subjects with chronic respiratory diseases such as asthma, emphysema, or cancer, obstructive pulmonary disease.
Trial design
Parallel
Treatments tested in this trial
High-intensity interval training
Other interventionThe intervention involves physical exercise with the aim of observing any changes that may occur in mental health and hormonal parameters. However, the magnitude of these effects and the type of exercise that is most effective in reducing symptoms of anxiety and depression are still unknown.
Moderate-intensity continuous training
Other interventionThe intervention involves physical exercise with the aim of observing any changes that may occur in mental health and hormonal parameters. However, the magnitude of these effects and the type of exercise that is most effective in reducing symptoms of anxiety and depression are still unknown.
Treatment groups
Trial outcomes
Primary outcomes
Symptoms of anxiety from baseline to eight weeks.
The measurement of anxiety symptoms will be conducted using the Beck Anxiety Inventory (BAI) in printed format, which is a validated psychological tool used to assess the severity of anxiety symptoms in adults. The total score is interpreted on a scale from 0 to 63, where a score of 0 indicates the absence of anxiety symptoms, and higher scores reflect increasing levels of anxiety, with the upper values representing severe anxiety.
Symptoms of depression from baseline to eight weeks.
The measurement of depression symptoms will be conducted using the Beck Depression Inventory (BDI) in printed format, which is a validated psychological tool used to assess the severity of depression symptoms in adults. The total score is interpreted on a scale from 0 to 63, where a score of 0 indicates the absence of depression symptoms, and higher scores reflect increasing levels of depression, with the upper values representing severe depression.
Testosterone levels using the ELISA method
Testosterone and cortisol levels will also be determined in picograms per milliliter (pg/mL) using the enzyme-linked immunosorbent assay (ELISA) method, which is employed to quantify hormones, cytokines, and other proteins in blood or other biological fluids.
Cortisol levels using the ELISA method
Cortisol levels will also be determined in picograms per milliliter (pg/mL) using the enzyme-linked immunosorbent assay (ELISA) method, which is employed to quantify hormones, cytokines, and other proteins in blood or other biological fluids.
Locations
Sponsors and contacts
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