Effects of Interrupting Prolonged Sitting With Different Standing Intervals on Vascular Health in Women
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age18-45
SponsorKing Saud University
About this trial
The goal of this clinical trial is to examine the effects of interrupting prolonged sitting with different standing intervals on vascular health in healthy women aged 18-45 years. The main questions it aims to answer are:
Does interrupting prolonged sitting with short standing intervals (10 minutes every hour) improve blood pressure and pulse wave velocity more than prolonged continuous standing intervals (30 minutes every hour)? Does interrupting prolonged sitting with prolonged intermittent standing intervals (30 minutes every hour divided into three 10-minute standing bouts) improve blood pressure and pulse wave velocity more than prolonged continuous standing intervals (30 minutes every hour)?
The researcher will compare three different sitting interruption conditions to evaluate their effects on vascular health outcomes:
Standing for 10 minutes every hour. Continuous standing for 30 minutes every hour. Intermittent standing for 30 minutes every hour divided into three 10-minute standing bouts.
Participants will:
Attend three experimental sessions in random order separated by at least 7 days.
Complete 3 hours of sitting with different standing interruption protocols. Undergo measurements of blood pressure, pulse wave velocity, and heart rate before sitting and after each hour of the experiment.
Undergo height, weight, and body mass index measurements.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
None
Disqualifiers
None
Trial design
Design model
Crossover
Treatments tested in this trial
Short Standing Interval
BehavioralParticipants will interrupt prolonged sitting with 10 minutes of standing every hour during 3 hours of sitting.
Continuous Standing Interval
BehavioralParticipants will interrupt prolonged sitting with 30 continuous minutes of standing every hour during 3 hours of sitting.
Intermittent Standing Interval
BehavioralParticipants will interrupt prolonged sitting with 30 minutes of standing every hour divided into three 10-minute standing bouts during 3 hours of sitting.
Treatment groups
24 Participants
are divided into 3 treatment groupsGroup A: Short Standing IntervalExperimental treatment 1 intervention
Group B: Continuous Standing IntervalExperimental treatment 1 intervention
Group C: Intermittent Standing IntervalExperimental treatment 1 intervention
Trial outcomes
Primary outcomes
1
Blood Pressure
Systolic and diastolic blood pressure will be measured before sitting and after each hour during the experimental sessions.
Time frame
Baseline, 1 hour, 2 hours, and 3 hours2
Pulse Wave Velocity
Time frame
Baseline, 1 hour, 2 hours, and 3 hours3
Heart Rate
Time frame
Baseline, 1 hour, 2 hours, and 3 hoursSponsors and contacts
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Source ClinicalTrials.gov