Effects of L-Tyrosine and Caffeine on Performance in Elite Boxers

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexMale
Age18+
SponsorInonu University

About this trial

Participants will complete six sessions, including one familiarization and baseline session followed by five experimental conditions: control (no supplementation), placebo, L-tyrosine, caffeine, and combined L-tyrosine plus caffeine. The experimental conditions will be performed in a randomized, counterbalanced crossover design with a washout period of at least 72 hours between sessions. Resting physiological and cognitive assessments will be performed during the familiarization session, while biochemical, cognitive, and boxing-specific performance assessments will be conducted before and after each experimental session.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

None

Disqualifiers

None

Trial design

Design model

Crossover

Treatments tested in this trial

  • Placebo

    Dietary supplement

    Placebo solution matched in taste and volume to active supplements.

  • L-Tyrosine

    Dietary supplement

    L-tyrosine at 150 mg/kg body weight administered 60 minutes before exercise.

  • Caffeine

    Dietary supplement

    Caffeine at 5 mg/kg body weight administered 60 minutes before exercise.

  • L-tyrosine + Caffeine

    Dietary supplement

    Combined L-tyrosine (150 mg/kg) and caffeine (5 mg/kg) administered 60 minutes before exercise.

Treatment groups

18 Participants
are divided into 5 treatment groups
Group A: PlaceboPlacebo comparator 1 intervention
Group B: L-tyrosineExperimental treatment 1 intervention
Group C: CaffeineExperimental treatment 1 intervention
Group D: CombinedExperimental treatment 1 intervention
Group E: ControlNo intervention 0 interventions

Trial outcomes

Primary outcomes

1

Stroop Test Performance

Cognitive performance assessed using the Stroop test, including reaction time and accuracy.

Time frame
up to 12 weeks

Secondary outcomes

1

BDNF Levels

Serum brain-derived neurotrophic factor levels measured before and after exercise.

Time frame
up to 12 weeks
2

Oxidative Stress Markers

Serum levels of total antioxidant status (TAS), total oxidant status (TOS), malondialdehyde (MDA), superoxide dismutase (SOD) activity, and glutathione peroxidase (GPx) activity will be measured.

Time frame
up to 12 weeks

Other outcomes

Sponsors and contacts

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Inonu University

Lead sponsor

Ataturk University

Collaborator

This trial is not recruiting at the moment. You can still explore other options: