At present, there are 290 million cardiovascular patients in China, including 11 million patients with coronary heart disease. Remote ischemic preconditioning(RIPC) may play an effective endogenous cardiac protection.This study will explore whether long-term use of RIPC in patients with AMI after PCI and non interventional therapy can reduce the incidence of major adverse cardiovascular cerebrovascular events(MACCE) and improve clinical outcomes and long-term prognosis.
Patients with acute myocardial infarction were diagnosed in accordance with the criteria of the "Global Unified Definition of Fourth Myocardial Infarction"
The patients could not tolerate RIPC or RIPerC
Aortic dissection, coronary artery aneurysm, coronary artery fistula and other systemic organic diseases
The uncontrolled systolic blood pressure and diastolic blood pressure of severe hypertension were 180 mmHg and 120 mmHg respectively
severe liver dysfunction (bilirubin > 20 mmol / L, prothrombin time > 2.0 ratio)
Parallel
RIPerC
Other interventionEach 40 minutes treatment time, 10 minutes as a cycle (cuff inflated to 200 mmHg and maintained for 5 minutes, then deflated for 5 minutes to start the next cycle), a total of 4 cycles
RIPC
Other interventionEach 40 minutes treatment time, 10 minutes as a cycle (cuff inflated to 200 mmHg and maintained for 5 minutes, then deflated for 5 minutes to start the next cycle), a total of 4 cycles
Rate of MACCEs
MACCE(include Cardiovascular death, non-fatal acute myocardial infarction, revascularization, stroke, admission due to heart failure )
Rate of Cardiovascular death events
Rate of Cardiovascular death events
Rate of non-fatal acute myocardial infarction events
Rate of non-fatal acute myocardial infarction events
Rate of revascularization events
Rate of revascularization events
Rate of stroke events
Rate of stroke events
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