Effects of Low-Level Laser Therapy and Hyaluronic Acid After Free Gingival Graft
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorAltinbas University
About this trial
The goal of this randomized clinical trial was to learn whether low-level laser therapy or hyaluronic acid application improves healing after free gingival graft surgery in adults with insufficient keratinized gingival tissue in the mandibular lower teeth region.
The main questions it aimed to answer were:
* Do low-level laser therapy and hyaluronic acid application reduce shrinkage of the gingival graft? * Do these treatments reduce postoperative pain and pain medication use and improve wound healing, clinical outcomes, appearance, and oral health-related quality of life?
Researchers compared three groups: free gingival graft surgery alone, free gingival graft surgery with low-level laser therapy and free gingival graft surgery with hyaluronic acid application.
Participants underwent free gingival graft surgery and were followed for six months. During follow-up, researchers measured graft size and shrinkage, periodontal clinical measurements, pain at the donor and recipient sites, pain medication use, wound healing, esthetic outcomes, and oral health-related quality of life.
Eligibility criteria
Qualifiers
Voluntary participation and provision of written informed consent
Systemically healthy adults aged 18 years or older
Non-smokers
No known drug allergies
Disqualifiers
Current use of medications that may interfere with wound healing or are contraindicated for surgical procedures
Pregnancy or breastfeeding
Ongoing orthodontic treatment in the affected region
History of previous periodontal surgery in the study area
Trial design
Treatments tested in this trial
- Topical Hyaluronic Acid Gel
- Low-Level Laser Therapy
- Free Gingival Graft Surgery
Treatment groups
30 Participants
are divided into 3 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov